1107579-37-2

Basic information

• Product Name: 3'-METHOXY-BIPHENYL-4-BORONIC ACID
• Synonyms: AKOS BRN-1042;3'-METHOXY-BIPHENYL-4-BORONIC ACID
• CAS NO: 1107579-37-2
• Molecular Formula: C13H13BO3
• Molecular Weight: 228.05152
• Mol File: 1107579-37-2.mol
• Article Data: 30

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3'-METHOXY-BIPHENYL-4-BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-METHOXY-BIPHENYL-4-BORONIC ACID(1107579-37-2)
• EPA Substance Registry System: 3'-METHOXY-BIPHENYL-4-BORONIC ACID(1107579-37-2)

Safety Data

• Hazardous Substances Data: 1107579-37-2(Hazardous Substances Data)

Usage

General Description

3'-Methoxy-biphenyl-4-borononic Acid, also known as Boronic Acid, 3'-Methoxy-1,1'-biphenyl-4-yl, is a chemical compound with the molecular formula C13H13BO3. 3'-METHOXY-BIPHENYL-4-BORONIC ACID belongs to the family of organic Boronic Acids and derivatives. Boronic acids, similar to this compound, are characterized by the presence of a boronic acid functional group which comprises one boron atom bonded to an oxygen atom and two hydrogen atoms. 3'-METHOXY-BIPHENYL-4-BORONIC ACID is often utilized in scientific research as they form stable covalent complexes with sugars, amino acids and hydroxamic acids. Applications of this compound may include pharmaceutical and agrochemical intermediate chemistry, as it has the potential to be used intricately in the synthesis of several chemical compounds. It is available for purchase for research use from several retailers in solid form. Precautions should be taken when handling this compound due to potential health hazards.

Upstream product

• 13195-76-1 triisobutyl borate 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 2398-37-0 3-methoxyphenyl bromide 
• 5419-55-6 Triisopropyl borate 
• 100-66-3 methoxybenzene 
• 121-43-7 Trimethyl borate 
• 73183-34-3 bis(pinacol)diborane 
• 7732-18-5 water 
• 13675-18-8 tetrahydroxydiboron 
• 157670-38-7 C₉H₁₃BO₃ 
• 325142-84-5 3-methoxyphenylboronic acid pinacol ester 

Downstream Products

• 56231-51-7 3-(3-methoxyphenyl)cyclohex-2-en-1-one 
• 2113-56-6 3-methoxybiphenyl 
• 71022-86-1 3′-methoxy-[1,1′-biphenyl]-4-ol 
• 128923-93-3 1‐(3‐methoxyphenyl)‐3‐nitrobenzene 
• 126485-58-3 3'-methoxy-[1,1'-biphenyl]-3-carboxaldehyde 
• 367268-90-4 2-(3-hydroxyphenyl)nitrobenzene 
• 438190-81-9 5-(3-methoxyphenyl)-2-aminobenzoic acid 
• 154848-38-1 3'-methoxy-[1,1'-biphenyl]-3-carbonitrile 
• 100261-25-4 tris(2-chloro-5-methoxy phenyl)boroxine 
• 1144519-88-9 C₁₈H₂₄N₂O₄ 

Relevant articles and documents

Mo–Catalyzed One-Pot Synthesis of N-Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent-Tuned Photophysical Properties

A catalytic domino reduction–imine formation–intramolecular cyclization–oxidation for the general synthesis of a wide variety of biologically relevant N-polyheterocycles, such as quinoxaline- and quinoline-fused derivatives, and phenanthridines, is reported. A simple, easily available, and environmentally friendly dioxomolybdenum(VI) complex has proven to be a highly efficient and versatile catalyst for transforming a broad range of starting nitroarenes involving several redox processes. Not only is this a sustainable, step-economical as well as air- and moisture-tolerant method, but also it is worth highlighting that the waste byproduct generated in the first step of the sequence is recycled and incorporated in the final target molecule, improving the overall synthetic efficiency. Moreover, selected indoloquinoxalines have been photophysically characterized in cyclohexane and toluene with exceptional fluorescence quantum yields above 0.7 for the alkyl derivatives.

Transition-Metal-Free Borylation of Aryl Bromide Using a Simple Diboron Source

In this study, we developed a simple transition-metal-free borylation reaction of aryl bromides. Bis-boronic acid (BBA), was used, and the borylation reaction was performed using a simple procedure at a mild temperature. Under mild conditions, aryl bromides were converted to arylboronic acids directly without any deprotection steps and purified by conversion to trifluoroborate salts. The functional group tolerance was considerably high. The mechanism study suggested that this borylation reaction proceeds via a radical pathway.

Synthesis and evaluation of sulfonamide derivatives as potent Human Uric Acid Transporter 1 (hURAT1) inhibitors

This letter presents synthesis and structure-activity relationship study of sulfonamide derivatives as inhibitors of Human Uric Acid Transporter 1 (hURAT1). Among all tested sulfonamide derivatives, compounds 9b, 16i and 19b exhibited excellent inhibition activity with IC50 value of 10, 2, and 83?nM, respectively. In addition, compounds 9b and 19b demonstrated moderate PK profile in rats.