1107601-70-6

Basic information

• Product Name: 1-Methyl-1H-pyrazole-4-methanamine hydrochloride
• Synonyms: 1-Methyl-1H-pyrazole-4-methanamine hydrochloride;(1-Methyl-1H-pyrazol-4-yl)MethanaMine hydrochloride;1H-Pyrazole-4-MethanaMine, 1-Methyl- (hydrochloride)(1:1);(1-Methyl-1h-pyrazol-4-yl)MethanaMine, HCl;(1-Methyl-1H-pyrazol-4-yl)MethaMine hydrochloride
• CAS NO: 1107601-70-6
• Molecular Formula: C5H9N3.HCl
• Molecular Weight: 147.606
• Mol File: 1107601-70-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-Methyl-1H-pyrazole-4-methanamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-1H-pyrazole-4-methanamine hydrochloride(1107601-70-6)
• EPA Substance Registry System: 1-Methyl-1H-pyrazole-4-methanamine hydrochloride(1107601-70-6)

Safety Data

• Hazardous Substances Data: 1107601-70-6(Hazardous Substances Data)

Usage

Description

1-Methyl-1H-pyrazole-4-methanamine hydrochloride, with the molecular formula C5H10N3·HCl, is a salt form of the organic compound 1-Methyl-1H-pyrazole-4-methanamine, also known as R(+)PZM21. This chemical compound is a potent and selective agonist at the μ-opioid receptor (MOR), exhibiting analgesic properties and a reduced potential for tolerance and dependence in preclinical studies. It is being explored as a novel opioid analgesic with the aim of offering reduced side effects and addiction liability compared to existing opioids. The hydrochloride salt form is favored in research for its enhanced stability and solubility in aqueous solutions.

Uses

Used in Pharmaceutical Industry:
1-Methyl-1H-pyrazole-4-methanamine hydrochloride is used as a research compound for the development of novel opioid analgesics. It is valued for its potential to provide effective pain relief while minimizing the risk of addiction and side effects associated with traditional opioids.
Used in Pain Management:
As a potent and selective μ-opioid receptor agonist, 1-Methyl-1H-pyrazole-4-methanamine hydrochloride is used for its analgesic effects, offering a promising alternative to conventional opioid medications in managing moderate to severe pain.
Used in Research Settings:
The hydrochloride salt form of 1-Methyl-1H-pyrazole-4-methanamine is utilized in research for its increased stability and solubility, facilitating studies on the compound's mechanism of action, efficacy, and safety profile in the context of pain management and opioid receptor modulation.