110763-40-1

Usage

Uses

Used in Organic Synthesis:
N-tert-Butoxycarbonyl-3-mercapto-L-valine is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure and functional groups enable the formation of diverse chemical compounds through a range of reactions.
Used in Peptide Chemistry:
In peptide chemistry, N-tert-Butoxycarbonyl-3-mercapto-L-valine is used as a building block for the synthesis of peptides. The Boc protecting group allows for the stepwise assembly of peptide chains, preventing unwanted side reactions and ensuring the correct sequence of amino acids.
Used in Pharmaceutical Development:
N-tert-Butoxycarbonyl-3-mercapto-L-valine is utilized in the development of pharmaceuticals, particularly in the synthesis of peptide-based drugs. Its versatility and reactivity make it a valuable component in the creation of novel therapeutic agents.
Used in Laboratory Research:
As a reagent in laboratory research, N-tert-Butoxycarbonyl-3-mercapto-L-valine is employed to study various chemical reactions and mechanisms. Its unique properties allow researchers to explore new synthetic routes and develop innovative methodologies in organic and peptide chemistry.

Upstream product

• 1113-41-3 L-penicillamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 34619-03-9 tert-butyldicarbonate 

Downstream Products

• 273401-74-4 3-benzylsulfanyl-2-tert-butoxycarbonylamino-3-methyl-butyric acid 

Relevant academic research and scientific papers

IAP ANTAGONISTS

There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

IAP ANTAGONISTS

There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

Aminosulf(ox)ides as Ligands for Iridium(I)-Catalyzed Asymmetric Transfer Hydrogenation

A new class of efficient catalysts was developed for the asymmetric transfer hydrogenation of unsymmetrical ketones. A series of chiral N,S-chelates (6-22) was synthesized to serve as ligands in the iridium(I)-catalyzed reduction of ketones. Both formic a

PEPTIDYL DERIVATIVES AS METALLOPROTEINASE INHIBITORS

Peptidyl derivatives are disclosed that are orally active metalloproteinase inhibitors. The peptidyl derivatives have a selective gelatinase action, have a long duration of action, and are useful in the prophylaxis or treatment of diseases or disorders in which stromelysis, collagenase or gelatinase have a role, for example, in the treatment of cancer to control the development of tumor metastases.

6-pen-vasopressin compounds

Vasopressin derivatives having unexpected VSP site binding activity whose structures are characterized by a Mpr unit at position 1 and a Pen unit at position 6 are prepared by standard peptide synthetic methods also using an oxidative cyclization of a linear peptide dimercaptan. A representative species is [1-β-mercaptopropionic acid-2-(O-ethyl)-D-tyrosine-4-valine-6-penicillamine-8-arginine]vasopressin.