110764-35-7

Usage

Uses

Used in Pharmaceutical Industry:
(2S,3'Z)-Cefprozil is used as an antibacterial agent for treating various bacterial infections. Its semisynthetic nature allows for targeted action against specific bacteria, making it a valuable component in the development of antibiotics to combat resistant strains.

Upstream product

• 106447-44-3 cis-7-amino-3-propen-1-yl-3-cephem-4-carboxylic acid 
• 107937-01-9 trans-7-amino-3-propen-1-yl-3-cephem-4-carboxylic acid 
• 337307-47-8 potassium (D)-N-[1-methoxycarbonylpropen-2-yl]-α-amino-p-hydroxyphenylacetate 

Relevant academic research and scientific papers

Process for preparation of 7-[alpha-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid

A process for preparation of 7-[D-α-amino-α-(4-hydroxyphenyl)acetamido]-3-(1-propen-1-yl)-3-cephem-4-carboxylic acid viz. Cefprozil of formula (I) igh purity, substantially free of impurities, which comprises preparation of mixed acid anhydride by selecting the sequence and temperature of addition of the reagents and its subsequent condensation with a protected 7-APCA; followed by hydrolysis, isolation and purification to give Cefprozil of formula (I) in the form of a monohydrate.

PROCESS FOR THE PREPARATION OF (Z)-ISOMER ENRICHED 7-AMINO-3-PROPEN-1-YL-3-CEPHEM-4- CARBOXYLIC ACID

The invention relates to a process for enrichment of the (Z)-isomer amount in a mixture of the (Z)- and (E)- isomers of 7-amino-3-(1-propen-1-yl)-3-cephem-4-carboxylic acid.