1107654-52-3Relevant academic research and scientific papers
Synthesis of sulfone-based nucleotide isosteres: Identification of CMP-sialic acid synthetase inhibitors
Wong, Jessica H.,Sahni, Urvashi,Li, Yanhong,Chen, Xi,Gervay-Hague, Jacquelyn
, p. 27 - 29 (2009)
A modular replacement approach to the synthesis of sulfo-nucleotide analogs prepared from condensation of nucleoside aldehydes with bis phosphonate Horner-Wadsworth-Emmons reagents is disclosed. These analogs were shown to be inhibitors of Neisseria menin
