1107658-75-2

Basic information

• Product Name: 1-pyrrolidinecarboxylic acid, 3-hydroxy-4-methyl-, 1,1-dimethylethyl ester, (3r,4r)-rel-
• Synonyms: 1-pyrrolidinecarboxylic acid, 3-hydroxy-4-methyl-, 1,1-dimethylethyl ester, (3r,4r)-rel-;(3R,4R)-rel-tert-Butyl 3-hydroxy-4-methylpyrrolidine-1-carboxylate;Cis-1-Boc-4-Methylpyrrolidin-3-Ol
• CAS NO: 1107658-75-2
• Molecular Weight: 0
• Mol File: 1107658-75-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-pyrrolidinecarboxylic acid, 3-hydroxy-4-methyl-, 1,1-dimethylethyl ester, (3r,4r)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-pyrrolidinecarboxylic acid, 3-hydroxy-4-methyl-, 1,1-dimethylethyl ester, (3r,4r)-rel-(1107658-75-2)
• EPA Substance Registry System: 1-pyrrolidinecarboxylic acid, 3-hydroxy-4-methyl-, 1,1-dimethylethyl ester, (3r,4r)-rel-(1107658-75-2)

Safety Data

• Hazardous Substances Data: 1107658-75-2(Hazardous Substances Data)

Usage

General Description

1-Pyrrolidinecarboxylic acid, 3-hydroxy-4-methyl-, 1,1-dimethylethyl ester, (3r,4r)-rel- is a chemical compound that belongs to the family of pyrrolidinecarboxylic acids. It is the t-butyl ester of (3R,4R)-3-hydroxy-4-methylproline. 1-pyrrolidinecarboxylic acid, 3-hydroxy-4-methyl-, 1,1-dimethylethyl ester, (3r,4r)-rel- is often used as a building block in organic synthesis and is commonly employed in the production of pharmaceuticals and agrochemicals due to its unique structural and steric properties. The (3R,4R)-stereochemistry of this compound is important for its biological activity, as it can influence its interaction with enzymes and receptors in living organisms.

Upstream product

• 216062-07-6 (2S,3R,6S)-6-(2-Hydroxy-1-methyl-ethyl)-2,3-diphenyl-morpholine-4-carboxylic acid benzyl ester 
• 73286-70-1 N-(tert-butoxycarbonyl)-3-pyrroline 
• 917-54-4 methyllithium 
• 114214-49-2 1-tert-butoxycarbonyl-3,4-epoxypyrrolidine 
• 143656-69-3 trans-4-methyl-3-pyrrolidinol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 216062-08-7 (1'R,3S,4S)-1-tert-butyloxycarbonyl-4-methyl-3-(1',2'-diphenylethoxy)pyrrolidine 

Downstream Products

• 885102-34-1 tert-butyl 3-methyl-4-oxopyrrolidine-1-carboxylate 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF

The present disclosure relates to inhibitors of one or more isoforms of RAS, such as inhibitors of one or more of KRAS, HRAS and NRAS, or mutants thereof, such as G12D, G12V, G13D or G12C mutants thereof. Therapeutic methods of treating conditions and dis

ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH AMINOALKOXY SUBSTITUTION

The invention relates to antibacterial compounds of formula I wherein R1a, R2a, R2b, R3a, R3b, R4, R5, U1, U2, U3, U4, V1, V2, V3, V4, X and Q and n are as defined in the specification. It further relates pharmaceutical compositions containing these compounds and the uses of these compounds in the manufacture of medicaments for the treatment of bacterial infections. These compounds are useful antimicrobial agents effective against a variety of human and veterinary pathogens including among others Gram-positive and Gram-negative aerobic and anaerobic bacteria.

PEPTIDE DEFORMYLASE INHIBITORS

The present invention is directed to certain {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide derivatives, compositions containing them, the use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity, and in the treatment of bacterial infections. Specifically, the invention is directed to compounds of formula (I), wherein R1, R2 and R3 are defined herein and to pharmaceutically acceptable salts thereof. The compounds of this invention are bacterial peptide deformylase inhibitors and can be useful in the treatment of bacterial infections.