110774-62-4Relevant academic research and scientific papers
Chiral amidophosphane-copper-catalyzed asymmetric conjugate addition of dialkylzinc reagents to nitroalkenes
Valleix, Fanny,Nagai, Kazushige,Soeta, Takahiro,Kuriyama, Masami,Yamada, Ken-Ichi,Tomioka, Kiyoshi
, p. 7420 - 7424 (2005)
The copper-amidophosphane-catalyzed asymmetric addition reaction of dialkylzinc reagents with β-aryl and β-alkylnitroalkenes afforded the corresponding nitroalkanes with moderate to good enantioselectivities (54-80% ee). The performance was highly dependent on the reaction procedure where the addition of nitroalkene to the mixture of copper-amidophosphane and dialkylzinc gave higher ee than the addition of dialkylzinc to a mixture of copper-amidophosphane and nitroalkene.
One-pot multi-substrate enantioselective conjugate addition of diethylzinc to nitroalkenes
Duursma, Ate,Minnaard, Adriaan J,Feringa, Ben L
, p. 5773 - 5778 (2007/10/03)
A multi-substrate approach is used in the copper-phosphoramidite catalyzed enantioselective conjugate addition of diethylzinc to nitroalkenes, using up to nine different nitroalkenes in a one pot procedure. The 18 products (9 times 2 enantiomers of nine d
Nitro Olefins and Organoaluminum Compounds: A Powerful Synthetic Tool in Organic Chemistry
Pecunioso, Angelo,Menicagli, Rita
, p. 2391 - 2396 (2007/10/02)
M species react with α-nitro olefins showing an unusual aptitude for a preferential transfer of saturated alkyl groups; M (R' = phenyl, benzyl, allyl) species, on the other hand, are able to transfer unsaturated groups with high chemosele
Efficient Conjugate Alkylation of α,β-Unsaturated Nitro Olefins by Triorganoalanes
Pecunioso, Angelo,Menicagli, Rita
, p. 45 - 49 (2007/10/02)
Both trialkylaluminum (AlR3; R = Et, i-Bu) and triorganoaluminum etherates (AlR3*OEt2; R = Et, i-Bu, Ph) rapidly react with α,β-unsaturated nitro olefins to give only 1,4-monoalkylated products in high yields.The natures of substrates, the reaction conditions as well as the reagents molar ratio, do not cause significant variations on the recovered products.
