110784-06-0Relevant academic research and scientific papers
Synthesis of cyclic imides (methylphtalimides, carboxylic acid phtalimides and itaconimides) and evaluation of their antifungal potential
Stiz, Dorimar,Corrêa, Rogério,D'Auria, Felicia D.,Simonetti, Giovanna,Cechinel-Filho, Valdir
, p. 647 - 654 (2016/10/18)
Background: This paper describes the synthesis of three different subfamilies of cyclic imides: methylphtalimides, carboxyl acid phtalimides and itaconimides. Methods: Fifteen compounds (five of each sub-family) were obtained by the reaction of appropriat
Mechanochemical synthesis of phthalimides with crystal structures of intermediates and products
Cola?o, Melwin,Dubois, Jean,Wouters, Johan
, p. 2523 - 2528 (2015/03/18)
A series of phthalimides have been successfully synthesized in the solid state by grinding (or kneading) of substituted phthalic anhydride and aniline derivatives. Selected products and intermediates were crystallized and characterized by crystallography leading to a potential rationale for the solid-state reactivity that suggests that co-crystals could serve as intermediates. This journal is
Design, synthesis, and structure-activity relationships of phthalimide- phenylpiperazines: A novel series of potent and selective {1a)-adrenergic receptor antagonists
Kuo, Gee-Hong,Prouty, Catherine,Murray, William V.,Pulito, Virginia,Jolliffe, Linda,Cheung, Peter,Varga, Sally,Evangelisto, Mary,Wang, Jian
, p. 2183 - 2195 (2007/10/03)
Beginning from the screening hit and literature α1-adrenergic compounds, a hybridized basic skeleton A was proposed as the pharmacophore for potent and selective α(1a)-AR antagonists. Introduction of a hydroxy group to increase the flexibility
