1108172-95-7

Upstream product

• 17342-08-4 (S)-Pyroglutaminol 
• 958457-61-9 tert-butyl (1S,2S,5R)-2-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate 
• 394734-88-4 ((1S,2S,5R)-3-benzyl-3-azabicyclo[3.1.0]hexan-2-yl)methanol 
• 220622-90-2 (3R,5aR,6aS,6bS)-3-phenyltetrahydro-3H-cyclopropa[3,4]pyrrolo[1,2-c]oxazol-5(1H)-one 
• 134107-65-6 (3R,7aS)-3-phenyl-3,7a-dihydro-1H-pyrrolo[1,2-c]oxazol-5-one 
• 103201-79-2 (3R,7aS)-3-phenyl-tetrahydro-pyrrolo[1,2-c]oxazol-5-one 
• 1108172-97-9 (1S,2S,5R)-2-(benzylamino-methyl)-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 

Downstream Products

• 1108173-00-7 (1S,2S,5R)-2-[(3-chloro-benzoylamino)-methyl]-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

BENZIMIDAZOLE-LINKED INDOLE COMPOUND ACTING AS NOVEL DIVALENT IAP ANTAGONIST

The present invention discloses a benzimidazole-linked indole compound acting as novel divalent IAP antagonist, specifically disclosing the compound shown in fomulas (I) or a pharmaceutically acceptable salt thereof.

TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES

The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.