1108185-09-6

Basic information

• Product Name: C₂₆H₂₅F₃N₄O₂
• CAS NO: 1108185-09-6
• Molecular Weight: 482.505
• Mol File: 1108185-09-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₅F₃N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₅F₃N₄O₂(1108185-09-6)
• EPA Substance Registry System: C₂₆H₂₅F₃N₄O₂(1108185-09-6)

Safety Data

• Hazardous Substances Data: 1108185-09-6(Hazardous Substances Data)

Upstream product

• 850033-39-5 4,4,5,5-tetramethyl-2-[2-methyl-4-(trifluoromethoxy)phenyl]-1,3,2-dioxaborolane 
• 1039826-64-6 (1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one-4-trifluoromethanesulfonate 

Relevant articles and documents

Synthesis and SAR of 4-aryl-1-(indazol-5-yl)pyridin-2(1H)ones as MCH-1 antagonists for the treatment of obesity

A new series of 4-aryl-1-(indazol-5-yl)pyridin-2(1H)ones possessing MCH-1 receptor antagonism is presented. Suzuki coupling of boronic acids with key triflate 6 allowed rapid generation of a range of analogs. The SAR of the MCH-1 receptor was explored with a variety of aryl and heterocyclic moieties. Selected compounds were studied in a five-day diet induced obese mouse model to evaluate their potential use as weight loss agents.