110822-74-7

Basic information

• Product Name: (2E,6Z)-(S)-4-Hydroxy-dodeca-2,6-dienal
• CAS NO: 110822-74-7
• Molecular Weight: 196.29
• Mol File: 110822-74-7.mol

Chemical Properties

• CAS DataBase Reference: (2E,6Z)-(S)-4-Hydroxy-dodeca-2,6-dienal(CAS DataBase Reference)
• NIST Chemistry Reference: (2E,6Z)-(S)-4-Hydroxy-dodeca-2,6-dienal(110822-74-7)
• EPA Substance Registry System: (2E,6Z)-(S)-4-Hydroxy-dodeca-2,6-dienal(110822-74-7)

Safety Data

• Hazardous Substances Data: 110822-74-7(Hazardous Substances Data)

Upstream product

• 127275-01-8 1-[(4S,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-(diphenyl-phosphinoyl)-2-morpholin-4-yl-ethanol 
• 127275-02-9 tert-Butyl-[(4S,5S)-2,2-dimethyl-5-((Z)-oct-2-enyl)-[1,3]dioxolan-4-ylmethoxy]-dimethyl-silane 
• 127275-00-7 [(4S,5S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-acetaldehyde 
• 127309-18-6 [(4S,5S)-2,2-Dimethyl-5-((Z)-oct-2-enyl)-[1,3]dioxolan-4-yl]-methanol 
• 127275-03-0 (4R,5S)-2,2-Dimethyl-5-((Z)-oct-2-enyl)-[1,3]dioxolane-4-carbaldehyde 
• 4762-26-9 hexyltriphenylphosphonium bromide 
• 127275-04-1 [(4S,5S)-2,2-Dimethyl-5-((Z)-oct-2-enyl)-[1,3]dioxolan-4-yl]-acetaldehyde 
• 110822-70-3 [(2R,3S)-((Z)-3-Oct-2-enyl)-oxiranyl]-acetaldehyde 

Downstream Products

• 54397-83-0 12-hydroxyeicosatetraenoic acid 

Relevant articles and documents

SYNTHESIS OF 12-HYDROPEROXYEICOSATETRAENOIC ACID (12-HPETE). ON THE STEROCHEMISTRY IN THE CONVERSION OF 12(S)-HETE TO 12-HPETE

12(S)-hydroxyeicosatetraenoic acid methyl ester 1 was synthesized. 1 was converted to phosphite 17 which upon treatment with hydrogen peroxide afforded the corresponding hydroperoxide 18 (12-HPETE methyl ester) with partially retained configuration.

ENANTIOSPECIFIC TOTAL SYNTHESIS OF 8- and 12-HYDROXYEICOSATETRAENOIC ACID

The R- and S-isomers of 8- and 12-hidroxyeicosatetraenoic acid (8- and 12-HETE) were synthesized from dimethyl malate derived precursors.