1108600-91-4Relevant academic research and scientific papers
Second-generation process for the hcv protease inhibitor biln 2061: A greener approach to ru-catalyzed ring-closing metathesis
Farina, Vittorio,Shu, Chutian,Zeng, Xingzhong,Wei, Xudong,Han, Zhengxu,Yee, Nathan K.,Senanayake, Chris H.
experimental part, p. 250 - 254 (2010/04/22)
The ring-closing metathesis (RCM) step, a key reaction in our process to BILN 2061, was dramatically improved from the first-generation process by the selection of a more appropriate substrate as well as the use of a more effective catalyst. The two RCM r
