110901-28-5 Usage
Derivative of tetralone
A bicyclic organic compound derived from the parent compound tetralone.
Flavonoid compound
A type of bioactive compound commonly found in plants, known for their antioxidant and anti-inflammatory properties.
Source
Roots of the plant Sophora flavescens
2,4,8-trihydroxy-1-tetralone is found in the roots of this plant species.
Antioxidant properties
The ability to neutralize free radicals and prevent oxidative stress, which can lead to various diseases and aging.
Anti-inflammatory properties
The capacity to reduce inflammation, which is a response to injury or infection in the body.
Potential pharmacological activities
The possibility of 2,4,8-trihydroxy-1-tetralone being used for various medical purposes.
Antitumor effects
The potential ability to inhibit the growth and spread of cancer cells.
Anti-HIV effects
The potential ability to inhibit the replication and activity of the Human Immunodeficiency Virus (HIV).
Neuroprotective effects
The potential ability to protect neurons from damage or degeneration, which can lead to neurological disorders.
Unique chemical structure
The specific arrangement of atoms and functional groups in 2,4,8-trihydroxy-1-tetralone that contributes to its biological activities.
Interest for further research and drug development
Due to its chemical structure and biological activities, 2,4,8-trihydroxy-1-tetralone is a promising target for future studies and potential use in the development of new drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 110901-28-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,9,0 and 1 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 110901-28:
(8*1)+(7*1)+(6*0)+(5*9)+(4*0)+(3*1)+(2*2)+(1*8)=75
75 % 10 = 5
So 110901-28-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H10O4/c11-6-3-1-2-5-7(12)4-8(13)10(14)9(5)6/h1-3,7-8,11-13H,4H2/t7-,8+/m0/s1
110901-28-5Relevant academic research and scientific papers
Asymmetric synthesis of the cis- and trans-3,4-dihydro-2,4,8-trihydroxynaphthalen-1(2H)-ones
Couche, Emmanuel,Fkyerat, Abdellatif,Tabacchi, Raffaele
, p. 210 - 221 (2007/10/03)
A short and efficient protocol for the asymmetric synthesis of cis- and trans-3,4-dihydro-2,4,8-trihydroxynaphthalen-1(2H)-one (1 and 2, resp.) is described, with a phthalide annulation as the key step. Introduction of a OH substituent at position 2 was performed by Sharpless dihydroxylation of a silyl enol ether or by means of an N-sulfonyloxaziridine. The absolute configuration of each isomer was determined via Mosherester derivatives. By comparison with previously recorded CD spectra of our natural sample, we established that the natural trans- and cis-isomers from Ceratocystis fimbriata sp. platani were the (-)-(2S,4S)-isomer (-)-2 and the (+)-(2S,4R)-isomer (+)-1, respectively.
