110911-12-1

Basic information

• Product Name: diethyl 5-cyano-2,4-pyridinedicarboxylate
• CAS NO: 110911-12-1
• Molecular Weight: 248.238
• Mol File: 110911-12-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 5-cyano-2,4-pyridinedicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 5-cyano-2,4-pyridinedicarboxylate(110911-12-1)
• EPA Substance Registry System: diethyl 5-cyano-2,4-pyridinedicarboxylate(110911-12-1)

Safety Data

• Hazardous Substances Data: 110911-12-1(Hazardous Substances Data)

Upstream product

• 617-35-6 2-oxo-propionic acid ethyl ester 
• 100-54-9 pyridine-3-carbonitrile 

Relevant articles and documents

HOMOLYTIC ALKOXYCARBONYLATION REACTIONS IN TWO-PHASE SYSTEMS 3. INTRODUCTION OF A SINGLE CARBOXYLIC ACID ESTER FUNCTION INTO CYANO- OR ALKOXYCARBONYL SUBSTITUTED N-HETEROAROMATICS

Homolytic alkoxycarbonylation reactions with cyanopyridines 1a, 2a, 3a, alkyl pyridinecarboxylates 1b, 2b, 3b, 3c and ethyl 4-pyridazinecarboxylate 4 in presence of dichloromethane were studied.It is demonstrated that under these conditions multiple substitution in general is suppressed markedly.Thus, this experimentally simple procedure represents an efficient and versatile method for single-step preparations of alkyl cyanopyridinecarboxylates 7a, 8a, 9a, 10a.Furthermore, it provides convenient access to so far not available mixed esters 5b, 7b, 8b, 10b, 13, derived from 2,3-pyridine-, 2,4-pyridine-, 3,4-pyridine and 4,5-pyridazinedicarboxylic acid.