110914-31-3Relevant academic research and scientific papers
Inter- and Intramolecular Hetero Diels-Alder Reactions, 36 Synthesis of Dihydropyrans by Hetero Diels-Alder Reaction of Enaminones An Efficient Route to 3-Amino Sugar Derivatives
Tietze, Lutz F.,Hartfiel, Uwe,Huebsch, Thomas,Voss, Edgar,Wichmann, Juergen
, p. 881 - 888 (2007/10/02)
The hetero Diels-Alder reaction of the N-monoacyl- and N,N-diacyl-enamino ketones 4a-g containing an electron-withdrawing group at C-2 of the oxadiene moiety with the electron-rich dienophiles 5a-d affords the diastereomeric adducts 6a-i and 7a-i in 78-98percent yield with the cis adducts 7a-i as the main products.The highest selectivity is obtained with the N,N-phthalimido-protected enamino ketones 4d-g.
