1109218-41-8Relevant articles and documents
2-Iminothiolane as a useful coupling reagent for polyamine solid-phase synthesis
Hahn, Frank,Müllen, Klaus,Schepers, Ute
experimental part, p. 2785 - 2790 (2009/05/07)
Here, the versatility of 2-iminothiolane to act as coupling reagent for solid-phase synthesis of polyamine conjugates is shown. This method, which supersedes the use of elaborate protection group strategies, allows the mild coupling of biomacromolecules and other functional moieties. Spermine conjugates with diverse maleimido building blocks were synthesized by a quick and selective reaction. Georg Thieme Verlag Stuttgart.