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1109277-49-7

Methyl 2-((1r,4r)-4-(4-(4-aMino-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1109277-49-7 Structure

  • Basic information

    1. Product Name: Methyl 2-((1r,4r)-4-(4-(4-aMino-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetate
    2. Synonyms: Methyl 2-((1r,4r)-4-(4-(4-aMino-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetate;Cyclohexaneacetic acid, 4-[4-(4-chloro-7,8-dihydro-5-oxopyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-, Methyl ester, trans-;trans-4-[4-(4-chloro-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6-(5H)-yl)phenyl]cyclohexyl}acetate ;Methyl {trans-4-[4-(4-chloro-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6-(5H)-yl)phenyl]cyclohexyl}acetate;HBUIVCMIRGZLMP-SHTZXODSSA-N
    3. CAS NO:1109277-49-7
    4. Molecular Formula: C22H24ClN3O4
    5. Molecular Weight: 410.46624
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1109277-49-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Methyl 2-((1r,4r)-4-(4-(4-aMino-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Methyl 2-((1r,4r)-4-(4-(4-aMino-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetate(1109277-49-7)
    11. EPA Substance Registry System: Methyl 2-((1r,4r)-4-(4-(4-aMino-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetate(1109277-49-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1109277-49-7(Hazardous Substances Data)

1109277-49-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1109277-49-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,9,2,7 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1109277-49:
(9*1)+(8*1)+(7*0)+(6*9)+(5*2)+(4*7)+(3*7)+(2*4)+(1*9)=147
147 % 10 = 7
So 1109277-49-7 is a valid CAS Registry Number.

1109277-49-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl {trans-4-[4-(4-chloro-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-(5H)-yl)phenyl]cyclohexyl}acetate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1109277-49-7 SDS

1109277-49-7Relevant articles and documents

Discovery of PF-04620110, a potent, selective, and orally bioavailable inhibitor of DGAT-1

Dow, Robert L.,Li, Jian-Cheng,Pence, Michael P.,Gibbs, E. Michael,Laperle, Jennifer L.,Litchfield, John,Piotrowski, David W.,Munchhof, Michael J.,Manion, Tara B.,Zavadoski, William J.,Walker, Gregory S.,McPherson, R. Kirk,Tapley, Susan,Sugarman, Eliot,Guzman-Perez, Angel,Dasilva-Jardine, Paul

scheme or table, p. 407 - 412 (2011/07/08)

Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) catalyzes the final committed step in the biosynthesis of triglycerides. DGAT-1 knockout mice have been shown to be resistant to diet-induced obesity and have increased insulin sensitivity. Thus, inhibiti

4-AMINO-5-OXO-7, 8-DIHYDROPYRIMIDO [5,4-F] [1,4] OXAZEPIN-6 (5H) -YL) PHENYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

-

Page/Page column 34, (2010/08/09)

The invention provides compounds of Formula (I), wherein R1, R2a, R2b, R3, m and A are as defined herein, as well as compositions thereof and methods for treating a disease, condition or disorder that is modulated by the inhibition of the diacylglycerol O-acyltransferase 1 (DGAT-1) enzyme by administering the compounds of the present invention and/or compositions thereof.

SUBSTITUTED BICYCLOLACTAM COMPOUNDS

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Page/Page column 13, (2009/03/07)

The invention provides compounds of formula (1), and the pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5a, R5b, R5c, R5d, Q, A, Z, and R7 /s

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