111008-09-4

Basic information

• Product Name: 3-Cyano-7-methyl-2-phenyl-indolizine-1-carboxylic acid methyl ester
• CAS NO: 111008-09-4
• Molecular Weight: 290.321
• Mol File: 111008-09-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Cyano-7-methyl-2-phenyl-indolizine-1-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyano-7-methyl-2-phenyl-indolizine-1-carboxylic acid methyl ester(111008-09-4)
• EPA Substance Registry System: 3-Cyano-7-methyl-2-phenyl-indolizine-1-carboxylic acid methyl ester(111008-09-4)

Safety Data

• Hazardous Substances Data: 111008-09-4(Hazardous Substances Data)

Upstream product

• 3189-57-9 4-methylpyridinium dicyanomethylide 
• 4891-38-7 phenylpropynoic acid methyl ester 

Relevant articles and documents

Regioselectivity in the 1,3-Dipolar Cycloaddition Reaction of Pyridinium Dicyanomethylides with Unsymmetric Alkynes

Representative pyridinium dicyanomethylides underwent regioselectively 1,3-dipolar cycloaddition onto methyl 3-trimethylsilyl-2-propynate and methyl 3-phenyl-2-propynate yielding the corresponding indolizines whereby 1-methoxycarbonylindolizines forms either exclusively or predominantly, in agreement with HOMO(ylide)-LUMO(dipolarophile) interaction as revealed by CNDO/2 calculation.