111011-79-1

Basic information

• Product Name: Efonidipine Hydrochloride
• Synonyms: (Z)-2-(Benzyl(phenyl)aMino)ethyl 3-aMinobut-2-enoate;3-Amino-2-butenoic acid 2-[phenyl(phenylmethyl)amino]ethyl ester;3-Amino-but-2-enoic acid 2-(benzyl-phenyl-amino)-ethyl ester;2-(N-benzylanilino)ethyl 3-aminobut-2-enoate;2-(benzyl(phenyl)amino)ethyl (Z)-3-aminobut-2-enoate;QUQRXEJGSOVLHO-PEZBUJJGSA-N
• CAS NO: 111011-79-1
• Molecular Formula: C19H22N2O2
• Molecular Weight: 310.39018
• EINECS: -0
• Mol File: 111011-79-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Efonidipine Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Efonidipine Hydrochloride(111011-79-1)
• EPA Substance Registry System: Efonidipine Hydrochloride(111011-79-1)

Safety Data

• Hazardous Substances Data: 111011-79-1(Hazardous Substances Data)

Usage

General Description

Efonidipine Hydrochloride is a type of pharmaceutical chemical compound primarily employed as an antihypertensive drug. It falls under the group of medications known as calcium channel blockers, which work by relaxing blood vessels, thereby reducing blood pressure and making it easier for the heart to pump blood. Efonidipine Hydrochloride inhibits both T- and L-type calcium channels, which makes it distinct from other calcium antagonists. Efonidipine Hydrochloride is primarily used in the management of angina and hypertension, and its usage can help prevent heart attacks, kidney problems, and strokes.

Related news

General paperEffects of Efonidipine Hydrochloride (cas 111011-79-1) (NZ-105), a new calcium antagonist, against acute renal failure in rats08/25/2019

1.1. We investigated the effect of efonidipine hydrochloride (NZ-105) against acute renal failure (ARF) in male Wistar rats. ARF was produced by ischemia or glycerol.2.2. Ischemia-induced ARF was produced by right nephrectomy and clamping of the left renal artery for 60 min, followed by reperfus...detailed

General paperRenal protective effect of Efonidipine Hydrochloride (cas 111011-79-1) (NZ-105), a new calcium antagonist, in spontaneously hypertensive rats08/24/2019

1.1. We investigated the renal protective effect of efonidipine hydrochloride (NZ-105) in spontaneously hypertensive rats (SHR). SHR were given a diet containing 0.075% NZ-105 from 8 weeks old for 20 weeks.2.2. 24-hr urinary protein excretion in the control SHR (drug-free diet) increased with ag...detailed

General paperEffects of Efonidipine Hydrochloride (cas 111011-79-1) (NZ-105), a calcium antagonist, on renal function in conscious spontaneously hypertensive rats08/23/2019

1.1. We investigated the effects of short- and long-term administration of efonidipine hydrochloride (NZ-105), 1,4-dihydropyridine derivative, in conscious spontaneously hypertensive rats (SHR).2.2. Oral administration of NZ-105 for 12 weeks caused diuretic and natriuretic effects, which were no...detailed

General PapersEffects of the Antihypertensive Drug Efonidipine Hydrochloride (cas 111011-79-1) on Albuminuria and Renal Histopathology in Young Spontaneously Hypertensive Rats with Diabetes08/22/2019

1.We investigated the renal protective effect of efonidipine hydrochloride (efonidipine, NZ-105) in STZ-induced spontaneously hypertensive rats (SHRs, 8 weeks of age). Diabetic SHRs were treated with 15 mg/kg/day of efonidipine for 12 weeks.2.The dosage of efonidipine was chosen after preliminar...detailed