111042-70-7

Basic information

• Product Name: (1R,3R,4S)-8-phenyl-p-menthan-3-yl (2R)-2-hydroxymethyl-3-methylbutyrate
• Synonyms: (1R,3R,4S)-8-phenyl-p-menthan-3-yl (2R)-2-hydroxymethyl-3-methylbutyrate
• CAS NO: 111042-70-7
• Molecular Weight: 346.51
• Mol File: 111042-70-7.mol

Chemical Properties

• CAS DataBase Reference: (1R,3R,4S)-8-phenyl-p-menthan-3-yl (2R)-2-hydroxymethyl-3-methylbutyrate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R,4S)-8-phenyl-p-menthan-3-yl (2R)-2-hydroxymethyl-3-methylbutyrate(111042-70-7)
• EPA Substance Registry System: (1R,3R,4S)-8-phenyl-p-menthan-3-yl (2R)-2-hydroxymethyl-3-methylbutyrate(111042-70-7)

Safety Data

• Hazardous Substances Data: 111042-70-7(Hazardous Substances Data)

Upstream product

• 111042-78-5 (1R,3R,4S)-8-phenyl-p-menthan-3-yl hydrogen isopropylmalonate 
• 601-79-6 isopropylmalonic acid 
• 65253-04-5 (-)-8-phenylmenthol 

Downstream Products

• 111042-72-9 (2S)-2,3-dimethylbutyl (S)-3,3,3-trifluoro-2-methoxy-2-phenylpropionate 
• 111042-74-1 (2S)-2-(dimethyl-t-butylsiloxymethyl)-3-methylbutyl (S)-3,3,3-trifluoro-2-methoxy-2-phenylpropionate 
• 15071-36-0 (R)-2,3-dimethylbutan-1-ol 
• 111042-80-9 (R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-methyl-butyric acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 

Relevant articles and documents

Asymmetric Syntheses of Chiral Propane-1,3-diols Starting from Malonic Acid

Syntheses of chiral intermediates having one tertiary asymmetric centre were carried out via chiral half-esters of monoalkylmalonic acids.The menthyl half-ester of ethylmalonic acid afforded a single diastereoisomer through crystallisation-induced asymmetric transformation (second-order asymmertic transformation).Furthermore enantioselective preparation of unsymmertical propane-1,3-diol derivatives was achieved by the use of 8-phenylmenthyl half-esters.

Enantioselective Synthesis of Useful Chiral Precursors, Unsymmetrical Propane-1,3-diol Derivatives, from Malonic acid

Syntheses of chiral synthons via monosubstituted malonic chiral half esters were studied and chiral 3-silyloxy propanols were enantioselectively synthesised.