111054-55-8 Usage
Description
1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-2-hydroxy-, ethyl ester, also known as ethyl 3,4-dihydro-2-hydroxy-1H-pyridine-4-carboxylate, is an organic compound that is a carboxylic acid ester and a derivative of pyridine. It is characterized by its potential applications in various industries, including pharmaceuticals, agrochemicals, and the production of flavor and fragrance compounds.
Uses
Used in Pharmaceutical Synthesis:
1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-2-hydroxy-, ethyl ester is used as an intermediate in the synthesis of pharmaceuticals for its potential therapeutic properties. It may contribute to the development of treatments for neurodegenerative diseases and certain types of cancer.
Used in Agrochemical Production:
In the agrochemical industry, 1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-2-hydroxy-, ethyl ester is used as a building block in the creation of various agrochemical products, potentially enhancing their effectiveness and performance.
Used in Flavor and Fragrance Compounds:
This chemical is also utilized in the production of flavor and fragrance compounds, where its unique properties can contribute to the development of novel and improved scents and tastes.
Safety Precautions:
It is important to handle 1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-2-hydroxy-, ethyl ester with caution, as it can be harmful if ingested or inhaled, and can cause skin and eye irritation. Proper safety measures should be taken during its use and storage to minimize potential health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 111054-55-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,0,5 and 4 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 111054-55:
(8*1)+(7*1)+(6*1)+(5*0)+(4*5)+(3*4)+(2*5)+(1*5)=68
68 % 10 = 8
So 111054-55-8 is a valid CAS Registry Number.
111054-55-8Relevant articles and documents
Facile Access to 6-Methoxy-1,2,3,6-tetrahydro- and 4-Hydroxy-1,2,3,4-tetrahydropyridines by Electrochemical Haloalkoxylation-Dehydrohalogenation Sequence as a Key Operation
Torii, Sigeru,Inokuchi, Tsutomu,Akahosi, Fumihiko,Kubota, Minoru
, p. 242 - 245 (2007/10/02)
A facile procedure for the synthesis of N-ethoxycarbonyl-6-methoxy-1,2,3,6-tetrahydropyridines 6 and N-ethoxycarbonyl-4-hydroxy-1,2,3,4-tetrahydropyridines 7 from piperidines 1 is described.The electrochemical halomethoxylation of N-ethoxycarbonyl-1,2,3,4-tetrahydropyridines 4 (easily accessible from 1 by ethoxycarbonylation followed by electrooxidative methoxylation and acid-catalyzed elimination of methanol) in a CH3OH-NR4X (X=Cl, Br, I)-(Pt)-(Pt) system provides N-ethoxycarbonyl-3-halo-2-methoxypiperidines 5 in 74-90percent yields.Dehydrohalogenation of iodides 5 (X=I)with 1,8-diazabicycloundec-7-ene (DBU) in toluene gave the desired olefin 6, which was isomerized in aqueous acetic acid to afford the alcohol 7 in 34-55percent yields (from 5).The procedure is also applicable to the synthesis of seven membered derivatives 6f and 7f from 1f.
