111055-92-6

Basic information

• Product Name: 6-chloro-9H-purine
• CAS NO: 111055-92-6
• Molecular Formula: C5H3ClN4
• Molecular Weight: 155
• Mol File: 111055-92-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-chloro-9H-purine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-9H-purine(111055-92-6)
• EPA Substance Registry System: 6-chloro-9H-purine(111055-92-6)

Safety Data

• Hazardous Substances Data: 111055-92-6(Hazardous Substances Data)

Usage

Type of compound

Purine derivative

Physical appearance

White to off-white crystalline powder

Solubility

Soluble in hot water, methanol, and ethanol

Uses

Intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes

Potential applications

Organic electronics and synthesis of biologically active compounds

Upstream product

• 4316-98-7 6-chloro-4,5-diaminopyrimidine 
• 122-51-0 orthoformic acid triethyl ester 
• 67-56-1 methanol 
• 7782-50-5 chlorine 
• 50-66-8 6-(methylthio)-1H-purine 
• 68-94-0 1,7-dihydro-6H-purin-6-one 

Downstream Products

• 1928-81-0 6-(piperidin-1-yl)purine 
• 525-81-5 (7(9)H-purin-6-yl)-[2]thienylmethyl-amine 
• 36412-32-5 octyl-(7(9)H-purin-6-yl)-amine 
• 6288-93-3 6-n-propylthiopurine 
• 26511-42-2 N-(7(9)H-purin-6-yl)-L-aspartic acid 
• 14814-48-3 heptyl-(7(9)H-purin-6-yl)-amine 
• 18917-30-1 6-(7(9)H-purin-6-ylamino)-hexan-1-ol 
• 6741-85-1 6-furfurylmercapto-7(9)H-purine 
• 7674-45-5 N₆-Cyclohexyladenine 
• 4217-23-6 (3-methyl-benzyl)-(7⁽⁹⁾H-purin-6-yl)-amine 
• 5443-87-8 6-isopropylmercapto-7(9)H-purine 
• 6312-66-9 6- purin 
• 16370-34-6 benzyl-methyl-(7⁽⁹⁾H-purin-6-yl)-amine 
• 99853-77-7 6-chloro-7-cyclohex-2-enyl-7H-purine 

Relevant articles and documents

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A One-Pot Synthesis of Highly Functionalized Purines

Highly substituted purines were synthesized in good to high yields through a one-pot straightforward metal-free scalable method, using the Traube synthesis adapted to Vilsmeier-type reagents. From 5-amino-4-chloropyrimidines, new 9-aryl-substituted chloropurines and intermediates for peptide nucleic acid synthesis were prepared. Variant procedures allowing a rapid synthesis of ribonucleosides and 7-benzylpurine from 5-amidino-6-aminopyrimidines are also reported to illustrate the high potential of this versatile toolbox. This route appears to be particularly interesting in the field of nucleic acids for a direct and rapid access to various new 8-alkylpurine nucleosides.