111072-24-3

Basic information

• Product Name: Hexanoic acid, 6-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-phenylpropyl]amino ]-, phenylmethyl ester, (S)-
• CAS NO: 111072-24-3
• Molecular Formula: C27H36N2O5
• Molecular Weight: 468.593
• Mol File: 111072-24-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Hexanoic acid, 6-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-phenylpropyl]amino ]-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanoic acid, 6-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-phenylpropyl]amino ]-, phenylmethyl ester, (S)-(111072-24-3)
• EPA Substance Registry System: Hexanoic acid, 6-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-phenylpropyl]amino ]-, phenylmethyl ester, (S)-(111072-24-3)

Safety Data

• Hazardous Substances Data: 111072-24-3(Hazardous Substances Data)

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 5515-01-5 benzyl 6-aminohexanoate 

Downstream Products

• 111053-02-2 Z-Phe-Phe-ε-Aca-OBzl 

Relevant articles and documents

Variation in Bitterness Potency When Introducing Gly-Gly Residue into Bitter Peptides

We previously reported that Gly-Gly-Arg-Pro and Arg-Pro-Gly-Gly, the derivatives of a bitter peptide Arg-Pro, had no bitterness although Gly-Arg-Pro and Arg-Pro-Gly had a bitter taste at the same level as that of Arg-Pro.To elucidate the mechanism of elimination of bitterness by the introduction of the Gly-Gly residues, we synthesized Gly-Gly derivatives of other bitter peptides such as Phe-Phe, Val-Val-Val, Arg-Pro-Phe-Phe, and examined the effectiveness of Gly-Gly residues in eliminating bitterness.We suggest that, for Arg-Pro and Val-Val-Val, the Gly-Gly residue might prevent a hydrophobic group from binding to a taste receptor.