111086-40-9Relevant academic research and scientific papers
Leukotriene Receptor Antegonist. 4. Synthesis and Leukotriene D4/E4 Receptor Antagonist Activity of 4-(Alkyl)acetophenone Derivatives
Gapinski, D. Mark,Roman, Carlos R.,Rinkema, Lynn E.,Fleisch, Jerome H.
, p. 172 - 175 (2007/10/02)
Analogues of the leukotriene D4/E4 receptor antagonist LY171883 (1a) were synthesized in which the tetrazole was linked to the hydroxyacetophenone moiety by an all-methylene carbon chain.A key step in the synthesis involved a Wittig
