1111072-24-2

Basic information

• Product Name: (E)-1-iodo-1-(4-butoxyphenyl)-3,3,3-trifluoropropene
• Synonyms: (E)-1-iodo-1-(4-butoxyphenyl)-3,3,3-trifluoropropene
• CAS NO: 1111072-24-2
• Molecular Weight: 370.153
• Mol File: 1111072-24-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-iodo-1-(4-butoxyphenyl)-3,3,3-trifluoropropene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-iodo-1-(4-butoxyphenyl)-3,3,3-trifluoropropene(1111072-24-2)
• EPA Substance Registry System: (E)-1-iodo-1-(4-butoxyphenyl)-3,3,3-trifluoropropene(1111072-24-2)

Safety Data

• Hazardous Substances Data: 1111072-24-2(Hazardous Substances Data)

Upstream product

• 1111072-16-2 1-butoxy-4-(3,3,3-trifluoroprop-1-ynyl)benzene 

Downstream Products

• 1111072-36-6 (E)-4-(4-butoxyphenyl)-N,N-diethyl-6,6,6-trifluorohex-4-en-2-yl-1-amine 
• 1111072-27-5 (Z)-1-(4-butoxyphenyl)-3,3,3-trifluoropropene 
• 1111072-37-7 (E)-4-(4-butoxyphenyl)-6,6,6-trifluorohex-4-en-2-yl-1-ol 
• 1111072-38-8 (E)-1-phenyl-3-(4-butoxyphenyl)-5,5,5-trifluoropent-3-en-1-yl 

Relevant articles and documents

Regio- and stereo-specific preparation of (E)-1-aryl-3,3,3-trifluoro-1-iodo-propenes and their palladium-catalyzed reaction with terminal alkynes

A new type of iodo-containing trifluoromethylated building blocks were synthesized. The reaction of 1-aryl-3,3,3-trifluoropropynes 1 with lithium iodide in acetic acid at 75 °C gave (E)-1-aryl-3,3,3-trifluoro-1-iodo-propenes 2 in high yield, which undergo the palladium-catalyzed Sonogashira reaction with terminal alkynes afforded trifluoromethyl-containing 1,3-enynes in high yield.