1111160-11-2Relevant academic research and scientific papers
Vinylogous Mannich-type reaction catalyzed by an iodine-substituted chiral phosphoric acid
Akiyama, Takahiko,Honma, Yasuhiro,Itoh, Junji,Fuchibe, Kohei
, p. 399 - 402 (2008)
2-Trimethylsiloxyfuran underwent a vinylogous Mannich-type reaction with aldimines under the action of a new chiral phosphoric acid, bearing iodine on the 6,6′-positions of the binaphthyl group, as a chiral Bronsted acid to give γ-butenolide derivatives bearing an amino functionality with high diastereo- and enantioselectivity.
