1111165-55-9Relevant academic research and scientific papers
Multicomponent reactions of pyridines, α-bromo carbonyl compounds and silylaryl triflates as aryne precursors: a facile one-pot synthesis of pyrido[2,1-a]isoindoles
Huang, Xian,Zhang, Tiexin
, p. 208 - 211 (2009)
Multicomponent reactions (MCRs) involving pyridines, α-bromo ketones, and silylaryl triflates as aryne precursors were investigated. The reactions could also be extended to isoquinoline or α-bromo ethyl acetate. Substituted pyrido[2,1-a]isoindoles or isoi
Novel synthesis of pyrido[2,1-a]isoindoles via a three-component assembly involving benzynes
Xie, Chunsong,Zhang, Yuhong,Xu, Peixin
experimental part, p. 3115 - 3120 (2009/06/05)
A novel three-component assembly involving benzynes has been developed for the synthesis of pyrido[2,1-a]isoindoles in moderate yields. Reaction conditions have been optimized and the scope of the reaction has been studied. A plausible mechanism has been proposed to account for the three-component reaction. Georg Thieme Verlag Stuttgart.
