111137-47-4Relevant academic research and scientific papers
Michael-Type Addition of O-Ethyl-C,O-bis(trimethylsilyl)ketene Acetal and its Application to the Synthesis of α-Ylidene-δ-lactones
Matsuda, Isamu
, p. 307 - 316 (2007/10/02)
O-Ethyl-C,O-bis(trimethylsilyl)ketene acetal behaves as an active C2 chainlenghtening unit when with α,β-unsaturated ketones yielding δ-keto-α-trimethylsilylesters with the aid of titanium tetrachloride.The products readily form α-ylidene-δ-lactone derivatives after selective reduction of the ketone carbonyl and subsequent Peterson type olefination.
