111163-24-7Relevant academic research and scientific papers
Design, synthesis and in vitro antiprotozoal activity of benzimidazole-pentamidine hybrids
Torres-Gomez, Hector,Hernandez-Nunez, Emanuel,Leon-Rivera, Ismael,Guerrero-Alvarez, Jorge,Cedillo-Rivera, Roberto,Moo-Puc, Rosa,Argotte-Ramos, Rocio,Carmen Rodriguez-Gutierrez, Maria del,Chan-Bacab, Manuel Jesus,Navarrete-Vazquez, Gabriel
, p. 3147 - 3151 (2008)
A series of ten novel hybrids from benzimidazole and pentamidine were prepared using a short synthetic route. Each compound was tested in vitro against the protozoa Trichomonas vaginalis, Giardia lamblia, Entamoeba histolytica, Leishmania mexicana, and Pl
Synthesis and biological evaluation of conformationally flexible as well as restricted dimers of monastrol and related dihydropyrimidones
Kamal, Ahmed,Shaheer Malik,Bajee, Shaik,Azeeza, Shaik,Faazil, Shaikh,Ramakrishna, Sistla,Naidu,Vishnuwardhan
experimental part, p. 3274 - 3281 (2011/08/03)
A series of conformationally flexible and restricted dimers of monastrol as well as related dihydropyrimidones have been synthesized by employing one-pot Biginelli multicomponent reaction. These dimers have been evaluated for cytotoxic potency against sel
Efficient synthesis of alkylene bridging bisdihydropyridines
Liu, Dong-Mei,Du, Li-Ting,Sun, Jing,Yan, Chao-Guo
experimental part, p. 1333 - 1338 (2010/06/21)
Under microwave irradiation, vanillin was alkylated with α,W-dihaloalkane to give 4,4'-alkylene-bridging vanillins, which in turn underwent one-pot multicomponent reactions with excess of ethyl acetoacetate and ammonium bicarbonate to give 4,4'-alkoxy-bri
Facile and efficient synthesis of the dimers of DC-81 antitumor antibiotics
Kamal,Rao
, p. 4299 - 4302 (2007/10/02)
We report an improved, economical and versatile route to the dimers of DC-81 anti-tumour antibiotics. Particularly, the protection and deprotection steps in its synthesis and in the preparation of its precursors have been avoided. There is a significant i
