1111641-75-8

Upstream product

• 13675-76-8 (E)-N-(3,4-dihydronaphthalen-1(2H)-ylidene)aniline 
• 13675-76-8 3,4-dihydro-1(2H)-N-phenylnaphtylimine 
• 62-53-3 aniline 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 

Relevant academic research and scientific papers

A mild dihydrobenzooxaphosphole oxazoline/iridium catalytic system for asymmetric hydrogenation of unfunctionalized dialins

Air-stable P-chiral dihydrobenzooxaphosphole oxazoline ligands were designed and synthesized. When they were used in the iridium-catalyzed asymmetric hydrogenation of unfunctionalized 1-aryl-3,4-dihydronaphthalenes under one atmosphere pressure of H2, up to 99:1 e.r. was obtained. High enantioselectivities were also observed in the reduction of the exocyclic imine derivatives of 1-tetralones.

L-Pipecolinic acid derived Lewis base organocatalyst for asymmetric reduction of N-aryl imines by trichlorosilane: Effects of the side amide group on catalytic performances

A series of N-formamides derived from pipecolinic acid have been synthesized and tested as Lewis base catalysts for the enantioselective reduction of N-aryl imines by trichlorosilane. Through the investigation of the structure-efficacy relationship between the side amide group and catalytic performance, several highly effective catalysts were discovered. In particular, arylamido-type catalyst 5i and non-arylamido-type catalyst 6c exhibited high reactivity and enantioselectivity, furnishing the reduction of a wide variety of N-aryl imines with high isolated yields (up to 98%) and ee values (up to 96%) under mild conditions. Moreover, these two catalysts complement each other in terms of their tolerances to nonaromatic ketimines and non-methyl ketimines. The Royal Society of Chemistry 2013.

Highly enantioselective iridium-catalyzed hydrogenation of trisubstituted olefins, α,β-unsaturated ketones and imines with chiral benzylic substituted P,N ligands

The benzylic substituted P,N ligands, diphosphinobenzyloxazolines, showed their high catalytic activity as well as asymmetric induction in the iridium-catalyzed asymmetric hydrogenation of unfunctionalized alkenes, α,β-unsaturated esters, allyl alcohols,

CATALYST COMPOUNDS

The present invention relates to compounds for use as catalysts, methods for producing said compounds and the use of said compounds as catalysts in catalytic processes including, but not limited to, the asymmetric reduction of imine and enamine compounds

Asymmetric reduction of ketimines with trichlorosilane employing an imidazole derived organocatalyst

Organocatalysts for the asymmetric reduction of ketimines are presented that function well at low catalyst loadings providing chiral amines in good yield and enantioselectivity, the latter appearing to be independent of the ketimine substrate geometry.