111187-15-6Relevant academic research and scientific papers
Chemoenzymatic synthesis and antimicrobial activity evaluation of monoglucosyl diglycerides
Cateni, Francesca,Bonivento, Paolo,Procida, Giuseppe,Zacchigna, Marina,Gabrielli Favretto, Luciana,Scialino, Giuditta,Banfi, Elena
, p. 815 - 826 (2007)
Monoglucosyl diglycerides with medium-long length fatty acid acyl chains were prepared and examined for antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. The study of their in vitro antimicrobial activity confirms the significant activity of some monoglucosyl diacylglycerol analogues and establishes for the glucose series that the 1,2-disubstitution and the octanoyl chain are the proper structural features for the maximum activity.
Chemoenzymatic synthesis and in vitro studies on the hydrolysis of antimicrobial monoglycosyl diglycerides by pancreatic lipase
Cateni, Francesca,Bonivento, Paolo,Procida, Giuseppe,Zacchigna, Marina,Scialino, Giuditta,Banfi, Elena
, p. 1971 - 1978 (2007)
Monoglucosyl and monogalactosyl diglycerides (MGDGs) with medium-long length acyl chains, identified as active components in Euphorbiaceae, were synthesized. They were examined for antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. MGDGs with two octanoyl groups at both 1- and 2-positions showed the most potent activity. The stereoselectivity of pancreatic lipase was investigated in vitro where the preference for the 1 position in MGDGs is strictly related to the length of the acyl chains.
Synthesis and anti-herpes simplex viral activity of monoglycosyl diglycerides
Janwitayanuchit, Wicharn,Suwanborirux, Khanit,Patarapanich, Chamnan,Pummangura, Sunibhond,Lipipun, Vimolmas,Vilaivan, Tirayut
, p. 1253 - 1264 (2003)
Based on the discovery of antiviral β-galactosyl diglycerides from Clinacanthus nutans leaves, 19 monoglycosyl diglycerides were synthesized and examined for inhibitory effect on herpes simplex virus types 1 and 2 (HSV-1, HSV-2). A study of the structure-
Chemoenzymatic synthesis and antimicrobial activity evaluation of monogalactosyl diglycerides
Cateni, Francesca,Bonivento, Paolo,Procida, Giuseppe,Zacchigna, Marina,Favretto, Luciana Gabrielli,Scialino, Giuditta,Banfi, Elena
, p. 210 - 221 (2008)
Monogalactosyl diglycerides with medium to long fatty acid acyl chains, were prepared and examined for antimicrobial activity against Gram positive, Gram negative bacteria and fungi. The study of their in vitro antimicrobial activity confirms the significant activity of some monogalactosyl diacylglycerol analogues and establishes for the galactose series that the 1,2-disubstitution and the octanoyl chain are the proper structural features for the maximum activity.
