111196-81-7

Basic information

• Product Name: 2-Chloro-5-ethylpyrimidine
• Synonyms: 2-CHLORO-5-ETHYLPYRIMIDINE;Pyrimidine, 2-chloro-5-ethyl- (9CI);2-chloro-5-ethylpyrimide;5-Ethyl-2-chloropyriMidin...;2-Chloro-5-ethyl-1,3-diazine, (2-Chloropyrimidin-5-yl)ethane;5-Ethyl-2-chloropyriMidine;2-Chloro-5-ethylpyriMidine, 97+%;2-Chloro-5-ethylpyrimidine,98%
• CAS NO: 111196-81-7
• Molecular Formula: C₆H₇ClN₂
• Molecular Weight: 142.59
• Product Categories: PYRIMIDINE;APIs & Intermediate;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Heterocycle-Pyrimidine series
• Mol File: 111196-81-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 18°C
• Boiling Point: 223 °C(lit.)
• Flash Point: >230 °F
• Appearance: Colorless to pale yellow/Liquid or Low Melting Solid
• Density: 1.174 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0363mmHg at 25°C
• Refractive Index: n20/D 1.521(lit.)
• Storage Temp.: Refrigerator
• PKA: -1.08±0.22(Predicted)
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 2-Chloro-5-ethylpyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5-ethylpyrimidine(111196-81-7)
• EPA Substance Registry System: 2-Chloro-5-ethylpyrimidine(111196-81-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 111196-81-7(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid or low melting solid

InChI:InChI=1/C6H7ClN2/c1-2-5-3-8-6(7)9-4-5/h3-4H,2H2,1H3

Upstream product

• 4212-49-1 5-ethyluracil 
• 97-93-8 triethylaluminum 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 34171-40-9 2,4-dichloro-5-ethylpyrimidine 

Downstream Products

• 545424-38-2 4-(5-Ethyl-2-pyrimidinyl)benzaldehyde 
• 934757-40-1 (2-[(5-ethyl-pyrimidin-2-yl)-(4-trifluoromethoxy-benzyl)-amino]-ethyl)-carbamic acid tert-butyl ester 
• 894400-06-7 2-(4-iodophenoxy)-5-ethylpyrimidine 
• 1054520-98-7 (S)-3-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)-5-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yl)-1,2,4-oxadiazole 
• 1272665-67-4 C₁₃H₁₃N₃O 
• 1391082-13-5 (4-{2-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-2,3-dihydro-benzofuran-5-yl}-phenyl)-morpholin-4-yl-methanone 
• 1318790-93-0 5-ethyl-2-[4-[5-(2,3-difluoro-4-methanesulfonylphenoxymethyl)pyrazin-2-yl]-3,6-dihydro-2H-pyridin-1-yl]pyrimidine 
• 1415818-49-3 4-((1r,4r)-4-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yloxy)cyclohexyloxy)nicotinonitrile 
• 1415991-86-4 5-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-2-[2-fluoro-4-(methylsulfonyl)phenyl]-1H-benzo[d]imidazole 
• 1415991-91-1 5-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-2-[2-fluoro-4-(methylsulfonyl)phenyl]benzo[d]oxazole 
• 1415991-42-2 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-5-[2-fluoro-4-(1H-tetrazol-1-yl)phenyl]benzo[d]oxazole 
• 1001397-30-3 4-{[1-(5-ethyl-2-pyrimidinyl)-4-piperidinyl]oxy}-7-[2-fluoro-4-(methylsulfonyl)phenyl]-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 
• 1416137-39-7 C₂₂H₂₇FN₆O₂S 

Relevant articles and documents

Trialkylalanes in palladium-catalyzed C-alkylations of azines

Carbo-substitution with alkyl groups in halogenoazines is readily effected under the influence of Pd-catalysis with alanes as the donor of the alkyl group. Acta Chemica Scandinavica 1997.

Pyri(mi)dyl-oxy-and -thio-benzoic acid derivatives useful as herbicides and plant growth regulants

New pyri(mi)dyl-oxy- or -thio-benzoic acid derivatives of the formula STR1 are taught which have herbicidal and plant growth regulating activity. In the formula Z can be Ch or N, X is oxygen or sulphur, A is oxygen, sulphur, a radical R5 --N=or a radical R6 O--N=and B is oxygen, sulphur, a radical STR2 with the proviso that at least one of the radicals R1, R2 or R3 represents alkyl or a part of a 3- to 6-membered fused carbocyclic ring.