111198-27-7

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 111198-09-5 [(benzotriazol-1-yl)-methyl]triphenyl phosphonium chloride 
• 603-35-0 triphenylphosphine 
• 54187-96-1 1-(chloromethyl)-1H-benzotriazole 
• 75295-55-5 diethyl ((1H-benzo[d] [1,2,3] triazol-1-yl)methyl)phosphonate 
• 2764-84-3 1-vinylbenzotriazole 
• 624-31-7 4-tolyl iodide 

Relevant academic research and scientific papers

A novel approach to the stereoselective synthesis of (E)-1- (1-Alkenyl)benzotriazoles

The Horner-Wadsworth-Emmons olefination of diethyl-(1- benzotriazolmethyl)phosphonate by means of aldehydes was found to be a convenient method for the stereoselective preparation of (E)-1-(1-Alkenyl)benzotriazoles.

Synthesis of N-(arylprop-2-en-1-yl)benzotriazoles by the Heck reaction

Various substituted 1-prop-2-en-1-ylbenzotriazoles react with aryl halides under Heck reaction conditions to give the corresponding alkenylbenzotriazole derivatives (10a-m). These are useful synthons for the preparation of dienes, β,γ-unsaturated ketones, alcohols and amines.

The Chemistry of N-Substituted Benzotriazoles. Part 1. 1-(Chloromethyl)-benzotriazole

The N-chloromethyl group of 1-(chloromethyl)benzotriazole undergoes nucleophilic substitution by carbon, nitrogen, phosphorus, oxygen, and sulphur nucleophiles. α-Lithiation was achieved in high yield in 1-phenylthiomethyl-, 1-phenylsulphinylmethyl-, and 1-(phenylsulphonylmethyl)benzotriazoles and the lithio derivatives reacted with a variety of electrophiles.New benzotriazolium salts were prepared by quaternization of the N-3 nitrogen with methyl iodide.