1112-12-5Relevant articles and documents
Heterogeneous Catalytic Hydration of α-Hydroxynitriles
Zil'berman, E. N.,Eremeev, I. V.
, p. 471 - 472 (2007/10/02)
In the hydration of α-hydroxyisobutironitrile and α-hydroxy-α-methylbutyronitrilr in the presence of manganese(IV) oxide we have detected an initial side-reaction: dehydrocyanation of the α-hydroxynitrile and adsorption of most of the resulting hydrocyanic acid on the catalyst surface, followed by addition of water to the unchanged α-hydroxynitrile with formation of an amide.The quantitative dependence of the yield of amide on the initial concentration of α-hydroxynitrile in the reaction mixture and the equilibrium constant of the dehydrocyanation have been calculated.