1112-94-3Relevant academic research and scientific papers
Ti(O-isoPr)4 Catalyzed hydrophosphonylation of activated alkenes by diphenyl H-phosphonate
Yao, Qiang
, p. 2749 - 2753 (2007)
Diphenyl 2-(alkoxycarbonyl)alkylphosphonates were synthesized via a titanium alkoxide catalyzed Pudovik reaction under mild conditions. Methacrylates or acrylates were selectively hydrophosphonylated by diphenyl H-phosphonate even in the presence of a dia
Comparison of catalytic activity of hexamethyltriamino- and tri-n-butylphosphines in the Pudovik reaction
Salin, Alexey V.,Il’in, Anton V.
, p. 355 - 356 (2019/01/04)
The catalytic activity of hexamethyltriaminophosphine in the P(O)–H bond addition to electron-deficient alkenes was studied. Depending on the nature of the alkene, hexamethyltriaminophosphine produces better or lower yields of the reaction products compared to tri-n-butylphosphine.
Generation of the Methoxycarbonyl Radical by Visible-Light Photoredox Catalysis and Its Conjugate Addition with Electron-Deficient Olefins
Slutskyy, Yuriy,Overman, Larry E.
supporting information, p. 2564 - 2567 (2016/07/06)
Visible-light photoredox-catalyzed fragmentation of methyl N-phthalimidoyl oxalate allows the direct construction of a 1,4-dicarbonyl structural motif by a conjugate addition of the methoxycarbonyl radical to reactive Michael acceptors. The regioselectivity of the addition of this alkoxyacyl radical species to electron-deficient olefins is heavily influenced by the electronic nature of the acceptor, behavior similar to that exhibited by nucleophilic alkyl radicals.
PS-BEMP as a basic catalyst for the phospha-Michael addition to electron-poor alkenes
Strappaveccia, Giacomo,Bianchi, Luca,Ziarelli, Simone,Santoro, Stefano,Lanari, Daniela,Pizzo, Ferdinando,Vaccaro, Luigi
supporting information, p. 3521 - 3525 (2016/04/19)
PS-BEMP was used as a heterogeneous catalyst for the phospha-Michael addition of phosphorus nucleophiles to a variety of electron-poor alkenes. The addition reactions were generally performed with equimolar amounts of reagents under solvent free conditions. The protocol proved to be very efficient for the addition to aromatic, non-aromatic and cyclic ketones, giving good yields (78-85%) in all cases. The protocol was also extended with good results to α,β-unsaturated esters and nitriles. This demonstrates that PS-BEMP is a good catalyst for the phospha-Michael addition to electron-poor alkenes.
A green procedure for the regio- and chemoselective hydrophosphonylation of unsaturated systems using CaO under solventless conditions
Martinez-Castro, Elisa,Lopez, Oscar,Maya, Ines,Fernandez-Bolanos, Jose G.,Petrini, Marino
supporting information; experimental part, p. 1171 - 1174 (2010/10/18)
Diethyl phosphite and diphenylphosphine add to a series of unsaturated derivatives using environmentally-friendly calcium oxide as a basic promoter under solventless conditions at room temperature. The corresponding adducts are obtained in a totally regio
One-pot synthesis of γ-hydroxy-γ-oxaphosphonates using pentacovalent oxaphosphorane chemistry
Hwang, Jae-Min,Islam, Tasneem,Jung, Kang-Yeoun
experimental part, p. 6076 - 6078 (2010/03/03)
P(V)-2,2,2-triethoxy-2,2-dihydro-5-methoxy-1,2λ5-oxaphospholene was synthesized as a new type of enolate which was hydrolyzed to give a series of phosphonates. In addition, aldol reaction of the oxaphospholene intermediate with several aldehyde
New inhibitors of rabbit muscle triose-phosphate isomerase
Fonvielle,Mariano,Therisod
, p. 2906 - 2909 (2007/10/03)
We describe the synthesis and evaluation of three new competitive inhibitors of triose-phosphate isomerase. One of them (phosphoglycoloamidoxime: Ki = 4.5 μM) is among the best reversible inhibitors so far reported for this enzyme.
1,5,7-Triazabicyclo[4.4.0]dec-1-ene (TBD), 7-methyl-TBD (MTBD) and the polymer-supported TBD (P-TBD): Three efficient catalysts for the nitroaldol (Henry) reaction and for the addition of dialkyl phosphites to unsaturated systems
Simoni, Daniele,Rondanin, Riccardo,Morini, Massimo,Baruchello, Riccardo,Invidiata, Francesco Paolo
, p. 1607 - 1610 (2007/10/03)
The 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) and its 7-methyl derivative (MTBD) have been proven to be of great synthetic utility as catalysts in the nitroaldol (Henry) reaction and for the addition of dialkyl phosphites to a variety of carbonyl compounds. The catalysts were in many cases superior to the parent tetramethylguanidine (TMG). In general the reaction proceeds in a few minutes at 0°C. The polymer-supported-TBD (P- TBD) was also proven to be an efficient promoter of the above cited nucleophilic additions. (C) 2000 Elsevier Science Ltd.
ACTIVATION ANIONIQUE DU PHOSPHITE DE DIETHYLE PAR LE FLUORURE DE POTASSIUM DEPOSE SUR ALUMINE, SYNTHESE DE PHOSPHONATES FONCTIONALISES
Villemin, Didier,Racha, Rassem
, p. 1789 - 1790 (2007/10/02)
Dry reactions of diethylphosphite on KF-AL2O3 with different electrophiles conduct to the synthesis of functionalized phosphonates.
