1112151-40-2Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of imidazole derivatives of some non-steroidal anti-inflammatory drugs
Parcha, Versha,Kaur, Jaswinder,Gupta, Vinay,Anroop
experimental part, p. 321 - 325 (2009/06/25)
A series of imidazole derivatives of NSAIDs (4a-l) have been prepared by condensation of NSAIDs hydrazides (1,2) with substituted oxazolones and evaluated for anti-inflammatory and gastrointestinal toxicity, which showed good anti-inflammatory activity and reduced gastrointestinal toxicity as compared to parent drug.
