111257-75-1Relevant academic research and scientific papers
Carbon Dioxide: A Reagent for the Simultaneous Protection of Nucleophilic Centres and the Activation of Alternative Locations to Electrophilic Attack. Part 8. A Novel Synthetic Route to 4-Substituted-2-pyridones
Katritzky, Alan R.,Fan, Wei-Qiang,Koziol, Anna E.,Palenik, Gus J.
, p. 2343 - 2348 (2007/10/02)
2-Pyridone, using the one-pot protection method, is lithiated specifically in the 4-position.In this way, a range of 4-substituted 2-pyridones was prepared.Their orientation of substitution was proved by X-ray analysis.
