1112975-92-4Relevant academic research and scientific papers
Remarkable efficiency improvement in the preparation of insoluble polymer-bound (IPB) enantioselective catalytic systems by the use of silicone chemistry
Mandoli, Alessandro,Lessi, Marco,Pini, Dario,Evangelisti, Claudio,Salvadori, Piero
, p. 375 - 379 (2008)
The use of platinum-catalyzed hydrosilylation chemistry of silicones greatly simplifies the preparation of bis-oxazoline (box) ligands covalently bound to an insoluble polymeric support. The use of such immobilized chiral ligands in different copper-catalyzed asymmetric transformations (carbonyl-ene, Mukaiyama aldol and olefin cyclopropanation reactions) allows the attainment of high levels of enantioselectivity (91-99% ee).
