111300-81-3

Basic information

• Product Name: 6-azacholest-4-en-3-ol-7-one
• Synonyms: 6-azacholest-4-en-3-ol-7-one
• CAS NO: 111300-81-3
• Molecular Formula: C26H43 N O2
• Molecular Weight: 401.63
• Mol File: 111300-81-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 558.3°Cat760mmHg
• Flash Point: 291.4°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 8.68E-15mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: 6-azacholest-4-en-3-ol-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-azacholest-4-en-3-ol-7-one(111300-81-3)
• EPA Substance Registry System: 6-azacholest-4-en-3-ol-7-one(111300-81-3)

Safety Data

• Hazardous Substances Data: 111300-81-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C26H43NO2/c1-16(2)7-6-8-17(3)19-9-10-20-23-21(12-14-25(19,20)4)26(5)13-11-18(28)15-22(26)27-24(23)29/h15-21,23,28H,6-14H2,1-5H3,(H,27,29)/t17?,18-,19+,20-,21-,23-,25+,26+/m0/s1

Upstream product

• 111464-86-9 3β-acetoxy-6-azacholest-4-en-7-one 
• 111331-23-8 C₃₀H₅₀O₇ 
• 809-51-8 7-ketocholesteryl acetate 

Relevant articles and documents

The Synthesis of some Cholesterol Derivatives as Probes for Mechanisms of Chlolesterol Metabolism

The syntheses of a series of cyclopropacholestanes, difluorocholestanes, and a ring B azacholestenone are described.Cyclopropacholestane-3,7-diols and their oxo derivatives were prepared from 3β-acetoxy-5α-cholest-5-en-7-one and a new route to 5α,6α-cyclopropacholestan-3β-ol was developed. 7,7-and 6,6-difluorocholestan-3-ols were obtained from fluorination of the acetoxy ketone precursors with sulphur tetrafluoride. 3β-Hydroxy-6-azacholest-4-en-7-one was prepared via the 3β-acetate by ozonolysis and ammonolysis of 3β-acetoxy-5α-cholest-4-en-7-one.The products have been used to study the mechanism of oxidation of cholest-5-en-3β-ol by its 7α-hydroxylase.