1113049-61-8 Usage
General Description
2-Amino-4-fluoro-5-hydroxy-benzoic acid methyl ester is a chemical compound that belongs to the class of benzoic acids. It is a derivative of salicylic acid and is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. 2-AMino-4-fluoro-5-hydroxy-benzoic acid Methyl ester is known for its potential biological activities, including anti-inflammatory and analgesic properties. Additionally, it has been studied for its potential use in the treatment of neurodegenerative diseases. Its methyl ester form makes it more stable and easier to handle, and it is often used in organic synthesis as a reagent for the preparation of other compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1113049-61-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,1,3,0,4 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1113049-61:
(9*1)+(8*1)+(7*1)+(6*3)+(5*0)+(4*4)+(3*9)+(2*6)+(1*1)=98
98 % 10 = 8
So 1113049-61-8 is a valid CAS Registry Number.
1113049-61-8Relevant articles and documents
Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype
Beaulieu, Pierre L.,Coulombe, René,Duan, Jianmin,Fazal, Gulrez,Godbout, Cédrickx,Hucke, Oliver,Jakalian, Araz,Joly, Marc-André,Lepage, Olivier,Llinàs-Brunet, Montse,Naud, Julie,Poirier, Martin,Rioux, Nathalie,Thavonekham, Bounkham,Kukolj, George,Stammers, Timothy A.
, p. 4132 - 4140 (2013/07/25)
We describe the structure-based design of a novel lead chemotype that binds to thumb pocket 2 of HCV NS5B polymerase and inhibits cell-based gt1 subgenomic reporter replicons at sub-micromolar concentrations (EC50 200 nM). This new class of po
VIRAL POLYMERASE INHIBITORS
-
Page/Page column 68, (2009/04/25)
Compound of Formula I: wherein, R2, R5 and R6 are defined herein, are useful as inhibitors of the hepatitis C virus NS5B polymerase
