111342-31-5

Basic information

• Product Name: 4-HYDROXYPHENOBARBITAL-D5
• Synonyms: 4-HYDROXYPHENOBARBITAL-D5;5-Ethyl-5-(4-hydroxyphenyl)-2,4,6(1H,3H,5H)-pyriMidinetrione-d5;5-Ethyl-5-(p-hydroxyphenyl)barbituric Acid-d5;NSC 159266-d5;p-Hydroxyphenobarbitone-d5;5-(4-hydroxyphenyl)-5-(1,1,2,2,2-pentadeuterioethyl)-1,3-diazinane-2,4,6-trione
• CAS NO: 111342-31-5
• Molecular Formula: C12H12N2O4
• Molecular Weight: 248.23468
• Product Categories: Isotope Labeled Compounds;Metabolites & Impurities;Isotope Labelled Compounds
• Mol File: 111342-31-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 223-224°C
• Appearance: /
• Storage Temp.: -20°C Freezer
• CAS DataBase Reference: 4-HYDROXYPHENOBARBITAL-D5(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXYPHENOBARBITAL-D5(111342-31-5)
• EPA Substance Registry System: 4-HYDROXYPHENOBARBITAL-D5(111342-31-5)

Safety Data

• Hazardous Substances Data: 111342-31-5(Hazardous Substances Data)

Usage

Description

4-HYDROXYPHENOBARBITAL-D5 is a labeled metabolite of Phenobarbital, which is an off-white solid. It is a compound that has been synthesized with deuterium (D5), a stable isotope of hydrogen, to serve various purposes in research and analysis.

Uses

Used in Pharmaceutical Research:
4-HYDROXYPHENOBARBITAL-D5 is used as a labeled metabolite for Phenobarbital in pharmaceutical research. The incorporation of deuterium allows for the study of the compound's metabolic pathways, pharmacokinetics, and pharmacodynamics, providing valuable insights into the drug's behavior in the body.
Used in Analytical Chemistry:
In the field of analytical chemistry, 4-HYDROXYPHENOBARBITAL-D5 is used as a labeled internal standard for the quantification and identification of Phenobarbital and its metabolites. The presence of deuterium in the compound enhances its stability and allows for more accurate measurements, improving the reliability of analytical results.
Used in Toxicology Studies:
4-HYDROXYPHENOBARBITAL-D5 is also used as a labeled reference compound in toxicology studies, helping researchers understand the toxic effects of Phenobarbital and its metabolites on various biological systems. This information can be crucial for assessing the safety and efficacy of Phenobarbital as a therapeutic agent.
Used in Drug Metabolism Studies:
In drug metabolism research, 4-HYDROXYPHENOBARBITAL-D5 serves as a labeled metabolite to investigate the metabolic processes of Phenobarbital. This can help researchers identify potential drug-drug interactions, predict the formation of toxic metabolites, and optimize drug dosages for improved therapeutic outcomes.