111380-29-1

Basic information

• Product Name: 1-{[3-(dimethylamino)propyl]amino}-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol
• Synonyms: 5H-pyrido[4,3-b]indol-8-ol, 1-[[3-(dimethylamino)propyl]amino]-4,5-dimethyl-
• CAS NO: 111380-29-1
• Molecular Formula: C₁₈H₂₄N₄O
• Molecular Weight: 312.4094
• Mol File: 111380-29-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 545.5°C at 760 mmHg
• Flash Point: 283.7°C
• Density: 1.19g/cm³
• Vapor Pressure: 1.64E-12mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 1-{[3-(dimethylamino)propyl]amino}-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{[3-(dimethylamino)propyl]amino}-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol(111380-29-1)
• EPA Substance Registry System: 1-{[3-(dimethylamino)propyl]amino}-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol(111380-29-1)

Safety Data

• Hazardous Substances Data: 111380-29-1(Hazardous Substances Data)

Upstream product

• 111380-50-8 4-methyl-8-methoxy-2H,5H-pyrido<4,3-b>indol-1-one 
• 111380-52-0 1-chloro-8-methoxy-4-methyl-5H-pyrido[4,3-b]-indole 
• 111380-54-2 1-chloro-4,5-dimethyl-8-methoxy-5H-pyrido[4,3-b]-indole 
• 111380-49-5 6,7,8,9-tetrahydro-8-methoxy-4-methyl-2H,5H-pyrido<4,3-b>indol-1-one 
• 95306-64-2 4-amino-5-methylpyridine-2(1H)-one 
• 111491-22-6 methyl-4 hydroxy-8-2H,5H-pyrido <4,3-b> indole-one-1 
• 111491-23-7 methyl-4 benzoyloxy-8-2H,5H-pyrido <4,3-b> indole-one-1 
• 111491-24-8 chloro-1 methyl-4 benzoyloxy-8-5H-pyrido <4,3-b> indole 
• 111491-25-9 chloro-1 dimethyl-4,5 benzoyloxy-8-5H-pyrido <4,3-b> indole 
• 106-51-4 p-benzoquinone 

Relevant articles and documents

Derivatives of pyridoindole, having anti-tumor properties

The present invention concerns derivatives of 5H-pyrido[4,3-b]-indole with the following general formula: STR1 in which n represents a whole number from 2 to 4, R1 represents hydrogen or a lower alkyl group; R2 represents hydrogen, a hydroxy group or a lower alkyloxy group; R3 and R4 represents hydrogen, a lower alkyl group or hydroxyalkyl group, R5 can be identical or different and represents hydrogen, a hydroxy group or a lower alkyl group, as well as the tautomeric forms and the addition salts with pharmaceutically acceptable mineral or organic acids. The invention also concerns their preparation process, and their use as medicaments.

SYNTHESE D'ANALOGUES TRICYCLIQUES DES ELLIPTICINES: LES METHYL-4,5H-PYRIDO INDOLES (γ-CARBOLINES) DIVERSEMENT SUBSTITUES SUR LEURS SOMMETS 1,5 ET 8.

Several ways to 1-functionnalized 4-methyl-5H-pyrido indoles have been worked out: a/ Starting from phenylhydrazines and 4-hydroxy-5-methyl-1H-pyridin-2-one 4 which react in boiling diphenylether giving directly 4-methyl-2H,5H-pyrido indol