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Syringomycin is a family of lipodepsipeptide antibiotics produced by certain strains of the bacterium Pseudomonas syringae. It exhibits a wide range of biological activities, including antimicrobial and antifungal properties. Known for its ability to disrupt the cell membranes of target microorganisms, leading to their destruction, Syringomycin has potential applications in agriculture for controlling plant pathogens and in medicine for treating infections. Its unique chemical structure and potent bioactivity make it a valuable and versatile tool in various fields of research and application.

11140-67-3

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11140-67-3 Usage

Uses

Used in Agriculture:
Syringomycin is used as a biocontrol agent for managing plant pathogens. Its antimicrobial properties help protect crops from various diseases caused by harmful microorganisms, thereby improving crop yield and quality.
Used in Medicine:
Syringomycin is used as an antimicrobial agent for treating infections caused by bacteria and fungi. Its ability to disrupt the cell membranes of these microorganisms makes it an effective treatment option for various infections.
Used in Research:
Syringomycin is used as a research tool for studying the mechanisms of action of lipodepsipeptide antibiotics. Its unique chemical structure and potent bioactivity provide valuable insights into the development of new antimicrobial agents and understanding the interactions between antibiotics and target microorganisms.
Used in Drug Development:
Syringomycin is used as a lead compound in the development of new antimicrobial and antifungal drugs. Its potent bioactivity and wide range of biological activities make it a promising candidate for the discovery of novel therapeutic agents to combat drug-resistant infections.

Check Digit Verification of cas no

The CAS Registry Mumber 11140-67-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,1,4 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 11140-67:
(7*1)+(6*1)+(5*1)+(4*4)+(3*0)+(2*6)+(1*7)=53
53 % 10 = 3
So 11140-67-3 is a valid CAS Registry Number.

11140-67-3Upstream product

11140-67-3Downstream Products

11140-67-3Related news

Requirement of sphingolipid α-hydroxylation for fungicidal action of syringomycin (cas 11140-67-3) E07/27/2019

Syringomycin E is an antifungal cyclic lipodepsinonapeptide produced by Pseudomonas syringae pv. syringae. To understand the mechanism of action of syringomycin E, a novel resistant Saccharomyces cerevisiae strain, BW7, was isolated and characterized. Lipid analyses revealed that BW7 contained o...detailed

The effect of sterols on the sensitivity of membranes to the channel-forming antifungal antibiotic, syringomycin (cas 11140-67-3) E07/25/2019

The ability of three sterols of different structure to influence the interaction of syringomycin E (an antifungal antibiotic that forms voltage dependent channels in planar lipid bilayers) with a planar lipid bilayer was evaluated. The rate of increase of bilayer conductance induced by syringomy...detailed

Role of ergosterol in growth inhibition of Saccharomyces cerevisiae by syringomycin (cas 11140-67-3) E07/23/2019

The antifungal activity of the lipodepsipeptide syringomycin E from Pseudomonas syringae pv. syringae is modulated by sterols. To study the requirement of the predominant fungal sterol, ergosterol, in syringomycin E action, the sterol composition of Saccharomyces cerevisiae sterol auxotroph stra...detailed

Channel-forming activity of syringomycin (cas 11140-67-3) E in two mercury-supported biomimetic membranes07/22/2019

The lipodepsipeptide syringomycin E (SR-E) interacts with two mercury-supported biomimetic membranes, which consist of a self-assembled phospholipid monolayer (SAM) and of a tethered bilayer lipid membrane (tBLM) separated from the mercury surface by a hydrophilic tetraethyleneoxy (TEO) spacer t...detailed

Structure of the lipodepsipeptide syringomycin (cas 11140-67-3) E in phospholipids and sodium dodecylsulphate micelle studied by circular dichroism, NMR spectroscopy and molecular dynamics07/20/2019

Syringomycin E (SRE) is a member of a family of lipodepsipeptides that characterize the secondary metabolism of the plant-associated bacteria Pseudomonas syringae pv. syringae. It displays phytotoxic, antifungal and haemolytic activities, due to the membrane interaction and ion channel formation...detailed

Lipid-mediated regulation of pore-forming activity of syringomycin (cas 11140-67-3) E by thyroid hormones and xanthene dyes07/21/2019

The effects of dipole modifiers, thyroid hormones (thyroxine and triiodothyronine) and xanthene dyes (Rose Bengal, phloxineB, erythrosin, eosinY and fluorescein) on the pore-forming activity of the lipopeptide syringomycin E (SRE) produced by Pseudomonas syringae were studied in a model bilayer....detailed

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