111423-08-6Relevant academic research and scientific papers
A facile microwave-assisted synthesis of some fused pyrimidine derivatives
Al-Issa
, p. 469 - 477 (2014/12/12)
The highly accelerated synthesis of thienopyrimidinones, theino- pyrimidines, thioxotheinopyrimidinones and a thienotriazolopyrimidinone derivatives under microwave irradiation is reported. Compared to conventional conditions, microwaves method offered se
Facile synthesis of 2-alkylthio-5,6,7,8-tetrahydrobenzothieno[2,3-d]- Pyrimidin-4(3H)-ones
Zeng, Xiao-Hua,Liu, Min,Ding, Ming-Wu,He, Hong-Wu
experimental part, p. 1453 - 1460 (2010/07/08)
Isothiocyanate 2, obtained from aza-Wittig reaction of iminophosphorane 1 with CS2, reacted with amine to give 2-thioxo-2,3,5,6,7,8- hexahydrobenzothieno[2,3-d]pyrimidin-4(1H)-ones 4 in the presence of sodium ethoxide. S-Alkylation of 4 produced 2-alkylth
Synthesis, characterization and biological studies of some novel thieno[2,3-d]pyrimidines
Al-Taisan, Khulud M.,Al-Hazimi, Hassan M. A.,Al-Shihry, Shar S.
experimental part, p. 3932 - 3957 (2010/09/18)
Several 2-unsubstituted thieno[2,3-d]pyrimidines have been prepared from 2-aminothiophene-3-carboxylic acid esters and their carbonitrile analogs. Some triazolothienopyrimidine and 2-thioxothienopyrimidine representatives have also been synthesized using
Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5
Wang, Ke,Li, Jinfeng,Degterev, Alexei,Hsu, Emily,Yuan, Junying,Yuan, Chengye
, p. 1455 - 1465 (2007/10/03)
Necrostatin-5 (Nec-5) is a novel potent small-molecule inhibitor of necroptosis structurally distinct from previously described Necrostatin-1 (Nec-1), and therefore, represents a new direction for the inhibition of this cellular caspase-independent necrot
Synthesis of some thienopyrimidine derivatives
El-Baih, Fatma E. M.,Al-Blowy, Hanan A. S.,Al-Hazimi, Hassan M.
, p. 498 - 513 (2007/10/03)
Thioxothienopyrimidinones, alkylthio- and arylalkylthiothienopyrimidinones, thienopyrimidinones, thienopyrimidines a thienopyrimidinedione and a thienotriazolopyrimidinone were prepared from 2-amino-3-carboethoxy-4,5- disubstituted thiophenes and 2-amino-
Interaction of heterothiocumulenes with 2-amino-3-cyanothiophenes: Formation of thienopyrimidines
Sukumaran, P.,Rajasekharan, K. N.
, p. 642 - 646 (2007/10/02)
Thieno-fused(1,3)-thiazine, 4-imino-2-thioxo-2,4-dihydro-1H-thieno(1,3)-thiazine (2) has been directly synthesised by the reaction of o-aminonitrile (1a) with carbon disulphide.Thiazine (2) on reaction with primary aromatic amines leads to thieno2
METHYL N-ARYLDITHIOCARBAMATES: USEFUL REAGENTS FOR THE ANNELATION OF PYRIMIDINES AND 1,3-OXAZINES TO FIVE-MEMBERED HETEROCYCLIC RINGS
Garin, Javier,Loscertales, Maria Pilar,Melendez, Enrique,Merchan, Francisco L.,Rodriguez, Ricardo,Tejero, Tomas
, p. 1303 - 1312 (2007/10/02)
The reaction of methyl N-aryldithiocarbamates with ?-excessive heteroaromatic o-amino acid derivatives leads to the annelation of 4-oxo-2-thioxopyrimidines, 2,4-dioxopyrimidines or 2-arylamino-1,3-oxazines, depending on the reaction conditions.
