111427-08-8

Basic information

• Product Name: 3-benzyl-4,5-dimethyl-1,3-thiazol-2(3H)-imine
• Synonyms: 3-benzyl-4,5-dimethyl-1,3-thiazol-2(3H)-imine
• CAS NO: 111427-08-8
• Molecular Weight: 218.323
• Mol File: 111427-08-8.mol

Chemical Properties

• CAS DataBase Reference: 3-benzyl-4,5-dimethyl-1,3-thiazol-2(3H)-imine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-4,5-dimethyl-1,3-thiazol-2(3H)-imine(111427-08-8)
• EPA Substance Registry System: 3-benzyl-4,5-dimethyl-1,3-thiazol-2(3H)-imine(111427-08-8)

Safety Data

• Hazardous Substances Data: 111427-08-8(Hazardous Substances Data)

Upstream product

• 78-93-3 butanone 
• 621-83-0 N-benzylthiourea 
• 33120-73-9 3-ethylthiazolin-2-thione 
• 111427-05-5 3-benzyl-4,5-dimethylthiazolin-2-one hydrazone 
• 111427-06-6 3-ethyl-4,5-dimethylthiazolin-2-one 
• 111427-04-4 3-benzylthiazolin-2-thione 
• 14779-10-3 μ-disulfido-1,2-diimido-dicarbonic acid bis-benzylamide; dihydrobromide 

Relevant articles and documents

Condensation of thiourea derivatives with carbonyl compounds: One-pot synthesis of N-alkyl-1, 3-thiazol-2-amines and of 3-alkyl-1, 3-thiazolimines

The reactions of ketones and AT-substituted thioureas, in the presence of HC1 (or HBr) and DMSO afford mixtures of the title compounds which are easily separated on a silica gel column. This method avoids the classical use of a-haloketones. The mechanism of these reactions involves the enolization of ketones and the activation of thiourea sulfur, probably by oxygen transfer from DMSO.

CARBENE VERSUS DIMER FORMATION FROM DIAZO DERIVATIVES: THE ANOMALOUS BEHAVIOUR OF 2-DIAZOTHIAZOLINES

Different oxidation procedures of 2-thiazolinone hydrazones, the anomalous behaviour of the resulting 2-diazothiazolines and a quantum-theoretical interpretation based in MNDO calculations are reported.