1114400-55-3Relevant academic research and scientific papers
Synthesis and application in SPPS of a stable amino acid isostere of palmitoyl cysteine
Cini, Elena,Lampariello, Lucia Raffaella,Rodriquez, Manuela,Taddei, Maurizio
experimental part, p. 844 - 848 (2009/04/07)
(S)-2-Amino-4-(2-pentadecyl-1,3-dioxolan-2-yl)-butanoic acid, 11, Pdiob, a synthetic analogue C-isostere of palmitoylated cysteine, has been prepared starting from tetrabenzyl glutamic acid. The less hindered benzyl carboxylate ester was transformed into
Transformation of glutamic acid into (S)-benzyl 2-(dibenzylamino)-6- (dimethoxyphosphoryl)-5-oxohexanoate for a convenient access to 5-substituted prolines
Cini, Elena,Giorgi, Gianluca,Rodriquez, Manuela,Taddei, Maurizio
experimental part, p. 1562 - 1566 (2009/11/30)
L-Glutamic acid was transformed into δ-keto-phosphonate in two steps. This compound was employed in the stereocontrolled synthesis of cis-5-substituted prolines through a Woodward-Horner-Emmons (WHE) reaction with different aldehydes followed by hydrogeno
