1114453-13-2Relevant academic research and scientific papers
Synthesis of thiadiazine, imidazothiadiazole, diazospiroundecatetraene and spirothiadiazolopyrimidinocyclohexadiene derivatives from 2,5-dithiobiureas
Hassan, Alaa A.,Aly, Ashraf A.,El-Sheref, Essmat M.
, p. 9 - 15 (2008/09/19)
Ethenetetracarbonitrile (2, in tetrahydrofuran solution), diethyl (E)-2,3-dicyanobutenedioate (10, in tetrahydrofuran solution), and 7,7′,8,8′-tetracyanoquinodimethane (16, in pyridine solution) act on 1-substituted-2,5-dithiobiureas 1a-c, forming the derivatives of imidazothiadiazole 5a-c, thiadiazine 11a-c and 12a-c, spiro(thiadiazolopyrimidino-cyclohexadiene)malononitrile17a-c and diazospiroundecatetraene18a-c. Rationales for these conversions involving the nucleophilic addition on diycanomethylene carbon atom are presented.
