1114474-89-3Relevant academic research and scientific papers
Discovery and optimisation of a potent and selective tertiary sulfonamide oxytocin antagonist
Barton, Nicholas P.,Bellenie, Benjamin R.,Doran, Andrew T.,Emmons, Amanda J.,Heer, Jag P.,Salvagno, Cristian M.
, p. 528 - 532 (2011/03/18)
The optimisation of a tertiary sulfonamide high-throughput screening hit is described. A combination of high-throughput chemistry, pharmacophore analysis and in silico PK profiling resulted in the discovery of potent sulfonamide oxytocin receptor antagoni
