111452-89-2

Basic information

• Product Name: 5-{3-[4-(4-Amino-benzenesulfonyl)-benzyloxy]-4-methoxy-benzyl}-pyrimidine-2,4-diamine
• Synonyms: 5-{3-[4-(4-Amino-benzenesulfonyl)-benzyloxy]-4-methoxy-benzyl}-pyrimidine-2,4-diamine
• CAS NO: 111452-89-2
• Molecular Weight: 491.571
• Mol File: 111452-89-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-{3-[4-(4-Amino-benzenesulfonyl)-benzyloxy]-4-methoxy-benzyl}-pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-{3-[4-(4-Amino-benzenesulfonyl)-benzyloxy]-4-methoxy-benzyl}-pyrimidine-2,4-diamine(111452-89-2)
• EPA Substance Registry System: 5-{3-[4-(4-Amino-benzenesulfonyl)-benzyloxy]-4-methoxy-benzyl}-pyrimidine-2,4-diamine(111452-89-2)

Safety Data

• Hazardous Substances Data: 111452-89-2(Hazardous Substances Data)

Upstream product

• 111452-96-1 5-{4-Methoxy-3-[4-(4-nitro-benzenesulfonyl)-benzyloxy]-benzyl}-pyrimidine-2,4-diamine 
• 100398-04-7 (4-bromomethyl-phenyl)-(4-nitro-phenyl)-sulfone 
• 83166-76-1 2,4-diamino-5-(3-hydroxy-4-methoxybenzyl)-pyrimidine 

Relevant articles and documents

Synthesis of new 2,4-diamino-5-benzylpyrimidines active against various bacterial species

New inhibitors of mycobacterial dihydrofolate reductase (DHFR) have been developed.These compounds show high inhibitory activities against Gram-negative and mycobacterial DHFR exceeding that for the commercially available DHFR blockers.Amongst these compo