111453-15-7Relevant academic research and scientific papers
Nucleophilic Functionalizations of Aniline Derivatives: Aromatic Pummerer Reaction for Umpolung Halogenation and Hydroxylation on Benzene Ring
Bao, Xingping,Yao, Jinzhong,Zhou, Hongwei,Xu, Guangyu
, p. 5780 - 5782 (2017)
In this paper, a metal-free protocol of nucleophilic ortho-halogenation and hydroxylation of anilines via an aromatic Pummerer process is reported.
Synthesis of new 2,4-diamino-5-benzylpyrimidines active against various bacterial species
Kansy, M,Seydel, JK,Wiese, M,Haller, R
, p. 237 - 244 (2007/10/02)
New inhibitors of mycobacterial dihydrofolate reductase (DHFR) have been developed.These compounds show high inhibitory activities against Gram-negative and mycobacterial DHFR exceeding that for the commercially available DHFR blockers.Amongst these compo
Substituted 2,4-diamino-5-benzylpyrimidines, their preparation and their use as medicaments with an antimicrobial activity
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, (2008/06/13)
Novel substituted 2,4-diamino-5-benzyl pyrimidines are described. The novel substances have antimicrobial activity and are particularly suitable for inhibiting the growth of mycobacteria. Combined with inhibitors such as diaminodiphenylsulphones, ring-substituted 4-aminodiphenylsulphones or ring and/or nitrogen-substituted diaminodiphenylsulphones, they have a marked synergistic activity.
